PHARM 4: Transgender

Question 1

Gender Incongruence vs. Gender Dysphoria?

Answer 1

Gender Incongruence: Disagreement w/ gender w/o distress

Gender Dysphoria: Distress associated with assigned gender

Question 2

Hormonal intervention for Medical transition?

Answer 2

Testosterone or Estrogen

• Estrogen alone can suppress gonadotropins a bit => circulating testosterone still leads to hair-growth/erections

Androgen blockage

• GnRH Analogues: Entirely hypogonadal, if on for more than 12 months => muscle/memory disabilities long term