Pharm. Flashcards

1
Q

Name an example of an oral contraceptive pill that is a combined, triphasic

A

Ethinyl estradiol/noregestimate

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2
Q

what is the trade name for ethinyl estradiol/noregestimate

A

Ortho Tricyclen Lo

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3
Q

What are the 2 indications for ethinyl estradiol/noregestimate

A

contraption and acne

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4
Q

what are the ADR’s of combined OCP’s

A

edema, wt. gain, bloating, GI disturbance, depression, amenorrhea, infertility, break-thru bleeding, breast tenderness/swelling/dx, worsening of menstrual migraines, thromboembolism

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5
Q

what are some DI’s to OCP’s

A

tobacco, transexamic acid (increases coagulation), some antivirals, abx

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6
Q

List an example of the combined, monophasic OCP

A

ethinyl estradiol/levonorgestrel

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7
Q

what is the trade name for ethinyl estradiol/levonorestrel

A

Alesse

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8
Q

give an example fo the OCP that has progestin only and is monophasic

A

Norethindrone

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9
Q

what is the trade name for norethindrone

A

ortho micronor

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10
Q

what is norethindrone’s indication

A

contraceptive for lactating women especially

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11
Q

what is the main MOA of norethindrone

A

thickens cervical mucus (22 hrs duration)

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12
Q

how strict is one need to take norethindrone ?

A

same time every day, miss by 3 hrs may cause bleeding

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13
Q

ADR’s of norethrindrone

A

nausea, HA, abnl menstrual cycle, breast tenderness, ectopic pregnancy

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14
Q

what is an example of an injectable contraceptive (progestin only)

A

medroxyprogesterone

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15
Q

what is the trade name for medroxyprogesterone

A

depo provera

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16
Q

where is the injection given and how often for medroxyprogesterone?

A

deltoid or gluteal region q 3 months.

17
Q

how long does it take after discontinuation of medroxyprogesterone for ovulation to occur

A

6-12 months, its the longest one

18
Q

ADR’s of medroxyprogesterone

A

injection site rxn, wt gain* abd pain, amenorrhea, spotting, reduced libido, fatigue, anaphylaxis, decreased bone density

19
Q

list an example of the intrauterine device, progestin only

A

levonorgestrel

20
Q

whats the trade name for levonorgestrel the IUD

21
Q

how often does levonorgestrel the IUD need to be replaced>

22
Q

list an example of the Menopause HT- transdermal patch

A

ethinyl estradiol patch aka Climara

23
Q

What do u add to the estrogen patch if the patient has a uterus?

A

progestin (combo patch climara pro)

24
Q

what are we using for urge incontinence?

A

oxybutynin a antispasmodic-antimuscarinic

25
what is the MOA of oxybutynin
competitive inhibits muscarinic receptors relaxing smooth muscle, particularly detrusor muscle
26
what are the ADR's of oxybutynin
anticholinergic effects, HS, seizures
27
what are the DI's for oxybutynin
CYP450 S, potassium, cholinesterase inhibitors, opiods, drugs that lower seizure threshold
28
why do we give the HPV vaccine and to what age group
prevents cancer to females age 11-12