Pharm. Flashcards

1
Q

Name an example of an oral contraceptive pill that is a combined, triphasic

A

Ethinyl estradiol/noregestimate

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2
Q

what is the trade name for ethinyl estradiol/noregestimate

A

Ortho Tricyclen Lo

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3
Q

What are the 2 indications for ethinyl estradiol/noregestimate

A

contraption and acne

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4
Q

what are the ADR’s of combined OCP’s

A

edema, wt. gain, bloating, GI disturbance, depression, amenorrhea, infertility, break-thru bleeding, breast tenderness/swelling/dx, worsening of menstrual migraines, thromboembolism

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5
Q

what are some DI’s to OCP’s

A

tobacco, transexamic acid (increases coagulation), some antivirals, abx

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6
Q

List an example of the combined, monophasic OCP

A

ethinyl estradiol/levonorgestrel

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7
Q

what is the trade name for ethinyl estradiol/levonorestrel

A

Alesse

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8
Q

give an example fo the OCP that has progestin only and is monophasic

A

Norethindrone

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9
Q

what is the trade name for norethindrone

A

ortho micronor

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10
Q

what is norethindrone’s indication

A

contraceptive for lactating women especially

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11
Q

what is the main MOA of norethindrone

A

thickens cervical mucus (22 hrs duration)

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12
Q

how strict is one need to take norethindrone ?

A

same time every day, miss by 3 hrs may cause bleeding

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13
Q

ADR’s of norethrindrone

A

nausea, HA, abnl menstrual cycle, breast tenderness, ectopic pregnancy

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14
Q

what is an example of an injectable contraceptive (progestin only)

A

medroxyprogesterone

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15
Q

what is the trade name for medroxyprogesterone

A

depo provera

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16
Q

where is the injection given and how often for medroxyprogesterone?

A

deltoid or gluteal region q 3 months.

17
Q

how long does it take after discontinuation of medroxyprogesterone for ovulation to occur

A

6-12 months, its the longest one

18
Q

ADR’s of medroxyprogesterone

A

injection site rxn, wt gain* abd pain, amenorrhea, spotting, reduced libido, fatigue, anaphylaxis, decreased bone density

19
Q

list an example of the intrauterine device, progestin only

A

levonorgestrel

20
Q

whats the trade name for levonorgestrel the IUD

A

mirena

21
Q

how often does levonorgestrel the IUD need to be replaced>

A

q 5yrs

22
Q

list an example of the Menopause HT- transdermal patch

A

ethinyl estradiol patch aka Climara

23
Q

What do u add to the estrogen patch if the patient has a uterus?

A

progestin (combo patch climara pro)

24
Q

what are we using for urge incontinence?

A

oxybutynin a antispasmodic-antimuscarinic

25
Q

what is the MOA of oxybutynin

A

competitive inhibits muscarinic receptors relaxing smooth muscle, particularly detrusor muscle

26
Q

what are the ADR’s of oxybutynin

A

anticholinergic effects, HS, seizures

27
Q

what are the DI’s for oxybutynin

A

CYP450 S, potassium, cholinesterase inhibitors, opiods, drugs that lower seizure threshold

28
Q

why do we give the HPV vaccine and to what age group

A

prevents cancer to females age 11-12