Breast Cancer Flashcards

1
Q

at what age are we beginning to screen for breast ca with a mammogram?

A

40

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2
Q

what puts someone at high risk for breast ca and when do we screen these pt?

A

family hx; 10 years b4 they were dx… other RF’s family hx of pancreatic ca, Ashkenazi jewish background

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3
Q

What other screening modalities are u going to consider for a women with denser breast tissue that makes mammograms less sensitive

A

US or MRI

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4
Q

when do we consider performing stereotactic bx

A

microcalcifications on US

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5
Q

how does the US help us evaluate a mass?

A

whether or not its cystic vs. solid

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6
Q

What do you do if you find a breast cyst that measures >2cm on U/S

A

stick a needle in it to aspirate…

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7
Q

When do you want to consider surgically excising a fibroadenoma?

A

If it is complex
Adjacent proliferative Dz
Family Hx of breast Ca

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8
Q

How will u tx a pt who u suspect has phyllodes tumor characterized as a very large aggressive FA

A

excise

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9
Q

Who is at increased risk for non-lactational breast abscess

A

smokers, obese, diabetics

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10
Q

how do u w/u a breast abscess

A

U/S Not mammogram

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11
Q

What charecteristics to the breast abscess would raise ur suspicion for anaerobic pathogen? What would u add to the abx regimen which should already cover for staph aureas.

A
  1. subareolar abscess
  2. retracted nipple
    Add Flagyl
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12
Q

which colors of nipple dx are usually benign? Concerning?

A

milky/green-benign

clear/bloody-concerning

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13
Q

How do u tx ductal carcinoma in situ

A

endocrine tx alone (no chemo) if at stage 0

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14
Q

when do u check axillary lymph nodes (sentinel nodes) for DCIS

A

when it’s high grade, lateral or large lesions, mastectomy

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15
Q

What is the breakdown in % of types invasive breast ca?

A

80% ductal
10% lobule
other 10%-
Favorable-intracystic, papillary, mucinous, tubular, medullary
Unfavorable-metaplastic, and angiosarcoma

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16
Q

what is an angiosarcoma

A

post-radiation tumor (unfavorable)

17
Q

This dz involves skin lesion of the nipple, is associated w/ DCIS

A

Paget’s dz

18
Q

IF you discover ur pt is Her2neu positive, what pharm. intervention could u imploy

A

Herceptin (trastuzamab) which is a monoclonal antibody

19
Q

How do we use molecular profiles via recurrence risk score to treat breast ca?

A

If low-endocrine therapy only
If High=add chemo
Intermediate-consider chemo

20
Q

Differentiate the two types of radiation for breast ca

A

External Beam- 4-6wks M-F

Brachytherapy: smaller lesions, neg. nodes, older age

21
Q

Define the TNM stages for breast ca

A
TX-not known
T0
T 5 stage 3 
Nodes: # involved 
Mets- stage 4 (skin involvement)
22
Q

what are F/U for lumpectomy vs. mastectomy

A

lumpectomy require mammogram q 6 months for 2 yrs. whereas no regular imaging required for mastectomy