Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

DEMS Unit 4 > Pharm > Flashcards

Pharm Flashcards

1
Q
  • Hypothryoid pregnant needs?
  • Thyroid meds take how long to equilibrate?
  • T4 –> T3 in periph blocked by? (3)
  • Graves treatment? (3) Drugs? (5)
  • Thyroid storm drugs? (4)
  • Young with hyper? Old?
A
  • T4 for fetus
  • 6-8 weeks
  • B-blockers, ipodate, corticosteroids
    1. ) Interfere with prod: Thionamides, Iodides
    2. ) Modify tissues: B Blockers/ Steroids
    3. ) Destroy: RAI
  • Propranolol, NaI, PTU, Hydrocortisone
  • Pharm; RAI
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Levothyroxine:

  • AKA?
  • Half life?
  • Ther. Window?
A
  • T4
  • Long
  • Narrow
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Liothyronine:

  • AKA?
  • Half life?
  • Risk of? (2)
A
  • T3
  • Short
  • Cardiac/osteoporosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Liotrix:

  • AKA?
  • SE?
A
  • 4:1 T4:T3

- Osteoporosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

USP:

  • AKA?
  • From where?
A
  • Variable T3/T4

- Pig extract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Methimaxole:

  • Drug type?
  • MOA? (2)
  • High dose?
  • SE? (4)
A
  • Thionamides
  • Block organo/ coupling
  • Lowers periph conversion
  • Pruritis, Arthralgias, Hepato, Agranulo
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

PTU:

  • Drug type?
  • MOA? (2)
  • High dose?
  • SE? (4)
A
  • Thionamides (Can use in pregnancy)
  • Block organo/ coupling
  • Lowers periph conversion
  • Pruritis, Arthralgias, Hepato, Agranulo
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Iodides:

  • MOA? (3)
  • Risk?
  • SE? (2)
A
  • Decrease hormone release via high IC iodide, Inhibits TGB proteolysis
  • Can make it worse
  • Rash, rhinorrhea
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q
  • GH Pharm:
  • Gherlin leads to?
  • GH increases? (2)
  • Somatostatin/ IGF1?
  • Nephrogenic DI can occur with? (3)
A
  • Release of GH
  • Insulin/ IGF-1
  • Decrease GH
  • Li, T2D, NSAIDS
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q
  • Sermorelin:
  • MOA?
  • Effectiveness?
A
  • Synthetic GHRH

- Not very

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q
  • Somatropin:
  • MOA?
  • Route?
A
  • Recomb. GH stim. IGF1

- IM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q
  • Somatrem:
  • MOA?
  • Route?
A
  • Recomb. GH stim. IGF1

- IM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q
  • Mecaserem:

- MOA?

A
  • GH resistant = IGF1 synthetic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q
  • Lanreotride:
  • MOA?
  • Decreases? (4)
  • Route?
  • Lasting?
A
  • Somatostatin analog
  • GH, Glucagon, Insulin, TSH
  • Sub Q
  • Long
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q
  • Octeotride:
  • MOA?
  • Decreases? (4)
  • Route?
  • Lasting?
A
  • Somatostatin analog
  • GH, Glucagon, Insulin, TSH
  • Sub Q
  • Long
  • Short
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q
  • Bromocriptine:
  • MOA?
  • Decreases? (2)
A
  • DA receptor agonist

- GH/ PRL

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q
  • Cabergoline:
  • MOA?
  • Decreases? (2)
  • Preferred?
A
  • DA receptor agonist
  • GH/ PRL
  • Yes
18
Q
  • Demecloclyine:
  • MOA?
  • Use?
A
  • Blocks vasopressin

- SIADH

19
Q
  • Desmopressin:
  • MOA?
  • Route?
A
  • Selective for V2 on kidney

- Nasal

20
Q
  • Vasopressin:
  • MOA?
  • Route? (3)
A
  • V1 (Gq) and V2 (Gs = exocytosis of aquaporins)

- SC/IM/IV

21
Q

Adrenal Pharm:

  • Effect of BK, Hist, Ach?
  • Pheo treatment? (2) Ex?
  • Ketone?
  • Hydroxy at 11?
  • Fludocortisone?
  • Dethamexasone?
  • 2 Cushing drop options?
  • Primary aldo? (2)
  • Androgen replacement?
A
  • Vasodilate
  • A block then B block; Phenoxybenzanine, Labatolol
  • Inactive
  • Active
  • All mineral
  • All gluco
  • Ketoconazole, Carbergiline
  • Spiranolactone, Eplenerone
  • DHEA
22
Q
  • Hydrocortisone MC:GC?
  • Prednisone MC:GC?
  • Methyprednisolone MC:GC?
  • Triamcinalone MC:GC?
  • Dexamethasone MC:GC?
A
  • 1:1
  • 4:1
  • 5:0
  • 5:0
  • 30:0
23
Q

Calcium Pharm:

  • Estrogen: 2 effects?
  • Vit D - 4 effects?
  • FGF23: 2 effects?
  • Hypercalcemia treatment? (3)
  • Hpocalcemia?
A
  • Increase OB OPG; decrease clasts
  • Increase PO4/Ca; Bone resorption, PO4 retention, lower PTH
  • PO4 wasting; Less vit D activation
  • Loop, IV, Bisphos.
  • IV calcium
24
Q
  • Cholecalcifirol:
  • AKA?
  • Preferred?
A
  • D3

- Yes

25
Q
  • Ergocalciferol:
  • AKA?
  • Preferred?
A
  • D2

- No

26
Q

Calcifidiol?

  • AKA?
  • Used for?
A
  • 25-D3

- Liver failure

27
Q

Calcitriol?

  • AKA?
  • Used for?
A
  • 1,25 D3

- Renal patients

28
Q

Dihydrotachysterol?

  • AKA?
  • Requires?
A
  • 1-D3

- 25 Hydroxy from liver

29
Q

Paracalcitol?

  • MOA?
  • Hypercalcemia?
A
  • D3 receptors on gland not intestine

- No

30
Q

Alendronate?

  • Drug type?
  • MOA?
  • Effective?
  • SE? (2)
A
  • Bispohosphanates
  • Pyrophos. to block OC’s
  • Yes
  • Esophagitis/GI
31
Q

Estrogen?

  • MOA? (2)
  • Use?
A
  • Increase OPG, lower OC’s

- Not much

32
Q

Raloxifine:

  • Drug type?
  • Act on? (4)
  • Increased risk of?
A
  • SERMS
  • Bone, liver, uterus, breast
  • Cancer
33
Q

Teriparatide:

  • Drug type?
  • MOA?
A
  • PTH analog

- Increase OB formation

34
Q

Calcitonin-salmon:

  • MOA?
  • Effective?
  • Route?
A
  • Inhibits OC
  • No
  • Nasal
35
Q

Denosumab:

  • Drug type?
  • MOA?
A
  • RANK-L Ab

- Lower OC activation

36
Q

HCTZ?

Flurosamide?

A
  • Increase serum Ca

- Decrease serum CA

37
Q
  • Tums/Calsup/Oscal:
  • Absorption?
  • SE? (2)
A
  • Low

- Antacid, Rebound

38
Q
  • Calcium Actetate:

- Use?

A
  • IV infusion for low Ca
39
Q
  • Calcium Gluconate:

- Use?

A
  • IV infusion for low Ca
40
Q
  • Calcium Chloride:

- Use?

A
  • IV infusion for low Ca but vein irritating
41
Q
  • Citracal:
  • AKA?
  • Recommended for?
A

Ca Citrate

- PPI users

DEMS Unit 4 (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions