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DEMS - Unit 1 > Pharm > Flashcards

Pharm Flashcards

1
Q
  • Tums:
  • Drug Type?
  • Use?
  • MOA?
  • SE? (4)
A
  • Antacids
  • GERD, PUD
  • Increase pH
  • Constip., rebound acid, Hypercalcemia, renal caliculi
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2
Q
  • Al + Something:
  • Drug Type?
  • Use?
  • MOA?
  • SE? (2)
A
  • Antacids
  • Widely used
  • Binds phosphate in gut to buffer
  • Const., CNS toxicity with chronic
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3
Q
  • Milk of Magnesia:
  • Drug Type?
  • Use?
  • MOA?
  • SE? (2)
A
  • Antacid
  • Conteract Al and Tums
  • Neutalize pH
  • Osmotic diarrhea, contra in renal dz
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4
Q
  • Baking Soda:
  • Drug Type?
  • Use?
  • MOA?
  • SE? (2)
  • Contra? (5)
A
  • Antacid
  • Potent
  • Evolution of CO2
  • Na overload, alkalosis
  • Pregnant, CHF, Htx, Edema, Renal
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5
Q
  • Scopolamine
  • Drug type?
  • Type?
  • Use?
  • MOA?
  • Efficacy?
  • SE?
A
  • Anti-secretory
  • M blocker
  • Motion sickness
  • M blocker
  • Large dose needed
  • Can’t see…
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6
Q
  • Rimantidine/Cimetidine
  • Drug type?
  • Type?
  • Use?
  • MOA?
  • Efficacy?
  • SE overall? (4)
  • CIM SE’s?
A
  • Anti-secretory
  • H2 Blocker
  • Gastritis, Nocturnal acid production
  • Reversible H2 block
  • Less than PPI’s
  • Dizzy, HA, COnstip, Diarrhea, decrease ketoconazole
  • CNS changes/ gynecomastia/cyp450
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7
Q
  • Omeprazole/Lasoprazole
  • Drug type?
  • Type?
  • Use?
  • MOA?
  • Efficacy?
  • SE?
  • Omep?
A
  • Anti-secretory
  • PPI
  • ZE/GERD/PUD
  • Luminal side attack of partietal cells
  • 80-95% reduction H+
  • Acid rebound, low Ca/Mg = bones/seizures
  • CYP activation of Clopedigrel
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8
Q
  • Misoprostol
  • Drug type?
  • Type?
  • Use?
  • MOA?
  • Efficacy?
  • SE?
A
  • Anti-secretory
  • PG analogue
  • NSAID induced
  • Low ph, increase mucus/bicarb
  • 4x/day
  • Contra in prego/uterine cramp
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9
Q
  • Sulfacrate
  • Drug type?
  • Use?
  • MOA?
  • Efficacy?
  • SE?
A
  • Anti-secretory
  • Ulcer Healing
  • Binds nectrotic tissue to heal with mucus; activated by H+ on empy stomach
  • 2-4x daily
  • Constipation
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10
Q

Cisparide:

  • Drug type?
  • Use? (3)
  • MOA?
  • SE?
A
  • Prokinetic
  • Achlasia, Gerd esophagitis, gastro par
  • Activates 5HT4 to increase ACH
  • Arrythmias!!! Increase QT interval
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11
Q

Metoclopramide:

  • Drug type?
  • Use? (3)
  • MOA?
  • SE?
  • Coordinated propel of? Blocks?
A
  • Prokinetic
  • Achlasia, Gerd esophagitis, gastro par
  • D2 Block to increase ACH
  • Tarditive, dystonia, somnelence
  • Lumin contents/ nausea
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12
Q
  • Meclizine/diphen
  • Drug type?
  • Use?
  • MOA?
  • SE?
A
  • Anti emetic
  • Motion sickness
  • H1 block at vestib. app
  • None
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13
Q

Metroclopramide

  • Drug type?
  • Use?
  • MOA?
  • SE?
A
  • Anti emetic
  • Chemo
  • D2 block chemo trigger zone
  • EPSE’s/ diarrhea
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14
Q

Ondansetron

  • Drug type?
  • Use?
  • MOA?
  • SE?
A
  • Anti emetic
  • Post-op/cyto drugs
  • Blocks 5HT at CTZ
  • HA/GI upset
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15
Q

Procerpazine

  • Drug type?
  • Use?
  • MOA?
  • SE?
A
  • Anti emetic
  • Chemo
  • D2 block chemo trigger zone
  • EPSE’s/ diarrhea
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16
Q

Psylium Seed

  • Type of drug?
  • Class?
  • Use?
  • MOA?
  • SE?
  • Guidelines?
A
  • Laxative
  • Fiber/bulk
  • Acute Constipation
  • Increase water and bulk
  • D-D interaction
  • 1st recommendation
17
Q

Mg(OH)2 - Polyethylene glycol

  • Type of drug?
  • Class?
  • Use?
  • MOA?
  • SE?
  • Guidelines?
A
  • Laxative
  • Saline cathartic
  • AC
  • Increase fluid volume
  • Decreases electrolytes
  • Added with fiber 2nd step
18
Q

Bisacodyl

  • Type of drug?
  • Class?
  • Use?
  • MOA?
  • SE?
  • Guidelines?
A
  • Laxative
  • Irritant/stimulant
  • AC/purging for food poison
  • Stim. enteric nerves
  • Abused/electro
  • Try if saline/fiber fail
19
Q

Docusate

  • Type of drug?
  • Class?
  • Use?
  • MOA?
  • SE?
  • Guidelines?
A
  • Laxative
  • Wetting agent
  • AC
  • Stool softener
  • Not in old/young
  • Used with opoid therapy
20
Q

Loperamide

  • Type?
  • Class?
  • MOA?
  • Abuse potential?
  • Use?
A
  • Anti-diarrheals
  • Opoid
  • H2O absorption
  • Low/ little CNS
  • Travellers Diarrhea
21
Q

Polycarbaphil

  • Type?
  • Class?
  • MOA?
  • Abuse potential?
  • Use?
A
  • Anti-diarrheals
  • Opoid
  • H2O absorption
  • Low/ little CNS
  • Travellers Diarrhea
22
Q

Bismuth/subsalicyclate

  • Type?
  • Class?
  • Does what?
  • Use?
A
  • Anti-diarrheals
  • Absorbant
  • Absorbs toxin, nutrients, etc
  • After each loose BM
23
Q

Koalin/Pectin

  • Type?
  • Does what?
  • Abuse potential?
  • Use?
A
  • Anti-diarrheals
  • Absorbant
  • Absorbs toxin, nutrients, etc
  • After each loose BM
24
Q

Tegasorad

  • Type?
  • Site?
  • MOA?
  • Used in?
  • SE? (4)
A
  • IBS
  • Stomach/SI
  • 5HT4 agonist to increase motility
  • Women under 55 with constipation
  • Early diarrhea, heart attack, stroke, angina
25
Q

Alsetron

  • Type?
  • Site?
  • MOA?
  • Used in?
  • SE? (2)
A
  • IBS
  • Colon
  • 5HT3 block to block coloinc motility
  • Women with severe IBS diarrhea
  • Constipation/Ischemic colitis

DEMS - Unit 1 (7 decks)

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