Pharm 2 Flashcards
Lithium indications and MOA
Mood stabilizer, first line for bipolar, interferes with ion transport, notable tremor
Lithium contraindications
Severe CV / renal disease, dehydration, sodium depletion
Lithium drug interactions
oodles, may enhance risk of QT prolongers
Valproate indications and MOA
Anti-seizure, migraine prophylaxis, mania, enhances GABA
Valproate side effects
headache, nausea, vomiting, tremor
Valproate contraindications
pregnancy or childbearing potential
Risperidone indications and MOA
antipsychotic, treatment of irritability/aggression with autism, blocks dopamine and serotonin receptors
Risperidone side effects
urinary retention, weight gain, seizure, sedation, extrapyramidals, postural hypotension, sexual dysfunction, arrhythmia, xerostomia
Imipramine indications
enuresis in children over 6, depression
Imipramine MOA
tricyclic antidepressant, inhibits dopamine and serotonin reuptake, also block serotonergic, alpha adrenergic, histaminic, and muscarinic receptors
Imipramine side effects
weight gain, xerostomia, constipation, urinary retention, blurry vision, tachycardia, arrhythmia, nausea, drowsiness
Imipramine contraindications
recent MI, MAOi’s within 14 days, linezolid, methylene blue
Desipramime indications and MOA
Tricyclic antidepressant, SNRI
List anticonvulsants
LOVEPC Lamotrigine Oxcarbazepine Valproate Ethosuximide Phenytoin Carbamazapine
fluoxetine indications and MOA
antidepressant, SSRI
bupropion indications and MOA
antidepressant, NDRI, fewer sexual side effects than SSRI
venlafaxine indications and MOA
antidepressant, SNRI
SSRI side effects
nausea, anxiety, drowsiness, insomnia, sexual dysfunction, drug interactions
tricyclic side effects
weight gain, xerostomia, constipation, urinary retention, blurry vision, tachycardia, arrhythmias, nausea, drowsiness
common side effects of antiseizures
ataxia, n/v, sedation, rash, weight changes, teratogen, hyponatremia, osteoporosis
phenytoin indications and MOA
generalized and tonic clonic antiseizure, blocks sodium channels
lamotrigine indications and MOA
wide variety of seizures and bipolar disorder, sodium channel and high voltage calcium blocker