PHARM Flashcards
1
Q
Heparin (HEP)
A
- anticoagulant
- aPTT = 30-40 sec
- therapuetic range = 1.5-2.5x normal = 46-70 sec
- ONLY anticoag safe in pregnancy!
- monitor for BLEEDING!
- antidote: Protamine sulfate
- complications: HITT (low platelets due to increased clotting)
2
Q
Warfarin
A
- anticoagulant
- INR/PT = 0.9-1.2 sec
- therapeutic range = 2-3 sec
- antidote: Vitamin K
- NEVER with the 4 G’s (ginger, garlic, ginseng, ginko biloba)
3
Q
Phenytoin
A
- antiseizure
- therapeutic level = 10-20
- SE: gingival hyperplasia!
- needs a filter!
- NO CALCIUM!
4
Q
Benzodiazepines (-zep- / -pams)
A
- sedatives/anti-anxiety
- treats seizures = Lorazepam
- antidote: Flumazenil
- Midazolam = fast-acting benzo
- Diazepam = long-acting benzo
5
Q
SSRIs (Fluozetine, Sertraline, Escitalopram)
A
- antidepressants
- increases serotonin
- SE: serotonin syndrome (HTN, confusion, anxiety, sweating)
- SUICIDE PRECAUTIONS for 2-3 weeks!
6
Q
TCAs (-triptyline)
A
- antidepressants
- increases norepinephrine + serotonin
- anticholinergic SE: can’t see/pee/spit/shit
7
Q
MAOIs (Isocarboxacid, Phenelezine, Tranylcypromine)
A
- antidepressant (IsoPheneTrany)
- increases all neurotransmitters
- SE: hypertensive crisis!
- NO TYRAMINE! (cheese, wine, avocaods)
8
Q
Lithium Carbonate
A
- mood stabilizer
- treats bipolar disorder!
- therapeutic range = 0.6-1.2
- SE: seizures, arrythmias, fatigue, confusion, nausea
- NO NSAIDs + DIURETICs
- AVOID dehydration
- not feeling well? take Lithium level + call MD!
9
Q
Haloperidol
A
- first-gen antipsychotic
- SE: EPS, tardive dyskinesia, NMS
- Extrapyramidal Symtpoms (EPS) = “Parkinson’s” tremors, slurred speech, dystonia, anxiety
- Tardive dyskinesia= involuntary repetitive moements (facial twitching, lip smacking, grimacing)
- Neuroleptic Malignany Syndrome (NMS) = “sunburnt white muscular guy” fever, muscle rigidity, altered LOC, increased WBCs
10
Q
-zine (Chlorpromazine)
A
- antipsychotic
ALL antipsychotics SE: EPS, NMS, tardive dyskinesia!
11
Q
Diphenhydramine (Benadryl)
A
- antihistamine (allergies)
- SE: drowsiness, anticholinergic SE, CNS depression
12
Q
Furosemide
A
- diuretic
- treats HF
- Na is exreted in urine
- BEFORE administering IV = check BP!
- SE: tinnitus (when pushed too fast)
- monitor K levels!
13
Q
Spironolactone
A
- Sp = Spares K+
- K-sparing diuretic
- treats HF + HTN
- monitor K levels!
14
Q
Hydrochlorothiazide
A
- (-thiazide) diuretic
- absorbs Na + water
- montor BP + electrolytes!
15
Q
ACE-Inhibitors (-pril)
A
- Lisinopril, Perindopril
- antihypertensive
- can causes COUGH + ANGIOEDEMA –> use ARBs instead!