pharm 1 Flashcards

1
Q

what the drug does to the body

A

pharmacodynamics

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2
Q

what body does to the drug (absorb, metab, etc)

A

pharmacokinetics

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3
Q

amt of drug that prod a therapeutic resp on 50% of people taking it

A

effective dose (ED)

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4
Q

amt of drug producing adverse effects in 50% of people taking it

A

toxic dose (TD)

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5
Q

dose w/i margin of safety between ED and LD

A

therapeutic dose/index

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6
Q

drugs can enter body thru GI tract aka _____ or thru a different means such as injecting, inhaling, transdermally, aka _____

A

enteral

parenteral

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7
Q

___ name describes a drugs atomic struct, ___ name is internationally recog, and ____ is the brand or trade name for a drug

A

chemical
generic
proprietary

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8
Q

____ drugs have high abuse pt’l and have no acceptable med use, ___ has high abuse pt’l but does have accepted med use - such as opium, morphine - amphets

A

CI

CII

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9
Q

____ drugs are by scrip only, include anabolic steroids, expire in 6 mo and have max 5 refills on one scrip

A

CIII

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10
Q
aminoglycosides
cephalosporins
fluroquinolones
penicillins
sulfonamides
tetracyclines
A

anti infectives

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11
Q

2 adverse rxn for aminoglycosides

A

ototoxic

nephrotoxic

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12
Q

cephalexin, keflex, ceftin, rochephin are all

A

cephalosoprins

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13
Q

ciprofloxacin aka cipro are _____, are antiobiot used for biowarfare and adverse rxn, while rare, include tendon rupture

A

fluoroquinolones

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14
Q

amoxicillin …w/ clavulanate aka augmentin, and ampicillin are ____ and adversely cause hypersens/photosens

A

penicillins

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15
Q

___ is a sulfonamide, used to tx systemic bact infx, but can cause photosens

A

bactrim

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16
Q

___ is a tetracycline, which can cause photosens

A

doxycycline

17
Q
a-adrenergic blockers
ACE inhibs
angiotensin II
beta blockers
ca-channel blockers
diuretics
A

anti-hypertensives

18
Q

lotensin, capoten, vasotec…all names with -pril are _____, can cause persistant DRY COUGH

A

ACE inhibs

19
Q

adverse rxn of beta-blockers, which reduce workload of heart (decr HR) includes weakness and

20
Q

atenoLOL, carvediLOL, metoproLOL, propranoLOL, sotaLOL are all

A

beta blockers

21
Q

diltiazem aka cardizem are ____, which relax sm musc => vasodilation

A

calcium channel blockers

22
Q

furosemide aka lasix is a ____, used for edema, htn, etc

23
Q

hydrochlorothiazide, HCTZ, is a thiazide which is a

24
Q

statins and bile acid sequestrants are used for

A

high cholest

25
drugs ending in -statin work by being ______, but can cause liver tox
hmg-coa reductase inhibs
26
metformin (glucophage) suppresses glucose prod by the liver for t2d, and adverse rxn is ___
flatulence
27
___ lower blood sugar by stim insulin release
sulfonylureas
28
narcotics benzos barbituates
sedatives
29
____ is an opioid used for diarrhea, and therefore can cause constipation and ___ ____
Lomotil | resp depression
30
___ is a mixed agonist-antagonism opioid
talwin
31
xanax, diazepam/valium, ativan, versed, or drugs ending in -PAM are all
benzos