pharm 1 Flashcards
what the drug does to the body
pharmacodynamics
what body does to the drug (absorb, metab, etc)
pharmacokinetics
amt of drug that prod a therapeutic resp on 50% of people taking it
effective dose (ED)
amt of drug producing adverse effects in 50% of people taking it
toxic dose (TD)
dose w/i margin of safety between ED and LD
therapeutic dose/index
drugs can enter body thru GI tract aka _____ or thru a different means such as injecting, inhaling, transdermally, aka _____
enteral
parenteral
___ name describes a drugs atomic struct, ___ name is internationally recog, and ____ is the brand or trade name for a drug
chemical
generic
proprietary
____ drugs have high abuse pt’l and have no acceptable med use, ___ has high abuse pt’l but does have accepted med use - such as opium, morphine - amphets
CI
CII
____ drugs are by scrip only, include anabolic steroids, expire in 6 mo and have max 5 refills on one scrip
CIII
aminoglycosides cephalosporins fluroquinolones penicillins sulfonamides tetracyclines
anti infectives
2 adverse rxn for aminoglycosides
ototoxic
nephrotoxic
cephalexin, keflex, ceftin, rochephin are all
cephalosoprins
ciprofloxacin aka cipro are _____, are antiobiot used for biowarfare and adverse rxn, while rare, include tendon rupture
fluoroquinolones
amoxicillin …w/ clavulanate aka augmentin, and ampicillin are ____ and adversely cause hypersens/photosens
penicillins
___ is a sulfonamide, used to tx systemic bact infx, but can cause photosens
bactrim
___ is a tetracycline, which can cause photosens
doxycycline
a-adrenergic blockers ACE inhibs angiotensin II beta blockers ca-channel blockers diuretics
anti-hypertensives
lotensin, capoten, vasotec…all names with -pril are _____, can cause persistant DRY COUGH
ACE inhibs
adverse rxn of beta-blockers, which reduce workload of heart (decr HR) includes weakness and
fatigue
atenoLOL, carvediLOL, metoproLOL, propranoLOL, sotaLOL are all
beta blockers
diltiazem aka cardizem are ____, which relax sm musc => vasodilation
calcium channel blockers
furosemide aka lasix is a ____, used for edema, htn, etc
diuretic
hydrochlorothiazide, HCTZ, is a thiazide which is a
diuretic
statins and bile acid sequestrants are used for
high cholest