adverse drug rxn, teratogens

Question 1

intxn bt MAO inhib and tyramine containing food, which is metab by MAO in GI tract
-causes htn, nausea, HA, stroke

Answer 1

cheese effect

Question 2

___ alters drug metab by cytochrome p450, rxn with antihistamines, benzos, emphetamines, caffeine, statins etc

Answer 2

grapefruit

Question 3

toxic epidermal necrosis from sulphur containing antibiotics

Answer 3

stevens johnson syndrome

Question 4

any agent that leads to a congenital anomaly or increases its incidence

Answer 4

teratogen

Question 5

class \_\_: known risk
class \_\_: contraindicated

Answer 5

D

X

Question 6

alcohol, cocaine, mercury, ibuprofen, tetracycline, are all

Answer 6

teratogens

Question 7

three teratogens

Answer 7

dilantin
thalidomide
warfarin/coumadin

Question 8

drug accumulates in endolymph and perilymph and damages hair cells, from aminoglycosides - antibiotics

Answer 8

ototoxicity

Question 9

vit __ is most teratogenic

Answer 9

A

Question 10

most toxic of all vitamins, in high doses

Answer 10

D

Question 11

vit causes cutaneous flushing, vasodilation

Answer 11

nacin/B3 tox

Question 12

___ is used for digitoxin

Answer 12

foxglove

Question 13

2 toxic plants

Answer 13

oleander - digitoxin

datura - anticholinergic toxidrome