Phagocytes:

Question 1

Manufactured in bone marrow.

Neutrophils:

Answer 1

Travel in the blood and squeeze out into the tissue fluid. They are short-lived and released in large numbers quickly as a result of an infection. Neutrophils die after digesting a few pathogens, collecting to form pus. Specialisations:

• Receptors on plasma membrane that can bind to opsonin or specific antigen.
• Multi-lobed nucleus that allows cell to squeeze through narrow gaps.
• Well-developed cytoskeleton that helps the cell change shape to engulf pathogens and move
  lysosomes around in the cell.
• Many lysosomes containing hydrolytic enzymes.
• Many mitochondria, to release energy from glucose for movement of cytoskeleton.
• Many ribosomes, to synthesise new enzymes involved.

Question 2

Macrophages:

Answer 2

Larger than Neutrophils and live longer, Kidney-bean shaped nucleus. Travel in the blood as monocytes, most in lymph nodes, where they mature into macrophages. Do not fully digest pathogens, form APCs.