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Phase 4 Endocrine > Phaeochromocytoma > Flashcards

Phaeochromocytoma Flashcards

1
Q

What is a phaeochromocytoma?

A

Catecholamine secreting tumour of the adrenal medulla. It is called a paraganglioma if it arises in sympathetic tissue elsewhere

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2
Q

What are the symptoms of a paraganglioma/phaochromocytoma?

A

Episodic hypertension,
Anxiety,
Weight loss,
Fatigue,
Palpitations
Sweating
Headaches
Flushing
Pyrexia
Dyspnoea
Abdominal pain

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3
Q

What are the signs of a phaeochromocytoma

A

Episodic Hypertension
Postural hypotension
Tremor
Hypertensive retinopathy

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4
Q

What are the investigations for a phaeochromocytoma?

A

Plasma metanephrines followed by 24 hour urinary metanephrines.
CR/MRI scan
Genetic testing

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5
Q

What is the treatment of a phaeochromocytoma?

A
  • Alpha blockade with phenoxybenzamine (to avoid hypertensive crisis in surgery)
  • Beta blockers for symptoms
  • Surgical ressection
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6
Q

What conditions are associated with a phaeochromocytoma?

A

MEN 2,
Neurofibromatosis 1
VHL syndrome

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Phase 4 Endocrine (19 decks)

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