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phA Flashcards

1
Q

diazepam

A

anxiolytics

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2
Q

alprazolam

A

anxyolitics

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3
Q

clonazepam

A

anxiolytics

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4
Q

nitrazepam

A

hypnotics

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5
Q

midazolam

A

hypnotics

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6
Q

flumazenil

A

non specific benzodiazepine R antagonist

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7
Q

zolpidem

A

non-BDZ hypnotic drugs

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8
Q

zaleplon

A

non-BDZ hypnotic drugs

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9
Q

buspirone

A

5-HT1A R partial agonist

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10
Q

melatonin

A

melatonin agonist to induce sleep

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11
Q

ramelteon

A

melatonin agonist to induce sleep
-activate MT1 and MT2 Receptors

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12
Q

SSRI

A

inhibits serotonin reupake in synaptic cleft to increase serotonin and SYM↓
-antidepressants

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13
Q

phenytoin

A

VG Na+ channel blocker for tonic clonic seizures

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14
Q

carbamazepine

A

VG Na+ channel blocker for epilepsy

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15
Q

phenobarbital

A

barbiturate
-VG Na+ channel blocker for epilepsy

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16
Q

vigabatrin

A

GABA transainase inhibitor

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17
Q

valproate

A

Na+ channel blocer
-GABA transaminase inhibitor for epilepsy

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18
Q

lamotrigine

A

Na+ channel blocker and glutamate release inhibition

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19
Q

levetiracetam

A

SV2A blocker for epilepsy

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20
Q

clonazepam

A

binds to BDZ receptor for absence seizures

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21
Q

ethosuximide

A

T-type Ca2+ channel blocker

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22
Q

diazepam

A

for status epilepticus

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23
Q

L-dopa

A

L-dopa conversion to dopamine by DOPA decaboxylase, for parkinsons

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24
Q

carbidopa

A

inhibitor of ODPA decarboxylase

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25
Q

ropinirole

A

dopamine agonists(non ergot)

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26
Q

pramipexole

A

dopamine agonists(non ergot)

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27
Q

entacapone

A

COMTi

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28
Q

amantadine

A

NMDA antagonist, inh of DA reuptake

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29
Q

memantine

A

nootropic, NMDA antagonist

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30
Q

seligiline

A

irreversible MAO-B inh

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31
Q

rivastigmine

A

cholinesterase inhibitors for alzheimer dementia

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32
Q

procyclidine

A

muscarinic R antagonist for parkinson

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33
Q

piracetam

A

nootropic drug for alzheimer/
SV2A blocker for parkinson disease like levetiracetam

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34
Q

tolcapone

A

COMTinh

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35
Q

diphenhydramine

A

H1 R antagonist (antihistamine)

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36
Q

promethazine

A

H1 R antagonist (antihistamine)

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37
Q

dimentindene

A

H1 R antagonist (antihistamine)

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38
Q

loratadine

A

H1 blocker antihistamine(2nd gen)

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39
Q

cetirizine

A

H1 blocker antihistamine(2nd gen)

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40
Q

fexofenadine

A

H1 blocker antihistamine(2nd gen)

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41
Q

desloratadine

A

H1 blocker antihistamine(3rd gen)

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42
Q

levocetirizine

A

H1 blocker antihistamine(3rd gen)

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43
Q

N-butylscopolamine

A

anticholinergic drug

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44
Q

solifenacin

A

anticholinergic

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45
Q

oxybutynin

A

anticholinergic M3 R blocker for bladder spasm

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46
Q

terbutaline

A

beta2-agonist

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47
Q

tamsulosin

A

alpha1 blocker

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48
Q

drotaverine

A

general smooth mm relaxants
VGCC blocker +papaverine

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49
Q

papaverine

A

general smooth mm relaxants

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50
Q

oxytocin

A

hypothalamc hormone

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51
Q

ergotamine

A

ergot alkaloid for postpartum hemmorahe and migraine

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52
Q

misoprostol

A

prostaglandins inducing labor
uterus contraction by PGE1 analogue

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53
Q

Mg2+, ethanol

A

drug affecting uterus

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54
Q

atosiban

A

oxytocin and ADH inhibitor for uterus

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55
Q

BOTUNInum toxin

A

cholinergic transmission inh(topic7) of the vesicular release of Ach

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56
Q

levodopa

A

adrenergic agonist

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57
Q

carbidopa

A

adrenergic agonist

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58
Q

carbachol

A

direct cholinergic agonists(M+N)

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59
Q

pilocarpine

A

cholinergic agonist(muscarinicM)

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60
Q

neostigmine

A

AchEsterase inh

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61
Q

pyridostigmine

A

AchEsterase inh

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62
Q

rivastigmine

A

AchEsterase inh

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63
Q

atropine

A

non selective cholinergic antagonists

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64
Q

cyclopentolate

A

non selective cholinergic antagonists

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65
Q

butyl-scopolamine

A

non selective cholinergic antagonists

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66
Q

procyclidine

A

non selective cholinergic antagonists

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67
Q

solifenacin

A

M3 R cholinergic antagonists

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68
Q

oxybutynin

A

M3 R cholinergic antagonists

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69
Q

ipratropium

A

non selective cholinergic antagonists

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70
Q

tiotropium

A

M3-R selective cholinergic antagonists

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71
Q

epinephrine

A

beta 1+2 R agonsists

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72
Q

NE

A

alpha 1, beta 1 R agonists

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73
Q

dopamine

A

D1-R agonists

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74
Q

isoprenaline

A

beta 1 and 2 R agonists

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75
Q

dobutamine

A

mostly beta 1 R agonist

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76
Q

phenylephrine

A

alpha 1R agonist

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77
Q

oxymetazoline

A

local alpha 1 R agonist

78
Q

clonidine

A

alpha 2 R agonist(auto R)
tizanidine=tizer=auto=alpha 2 r agonist is also a friend
-used in Tourettes syndrome!!

79
Q

rilmenidine

A

alpha 2 R agonist(auto R)
reel(ril) is auto=alpha 2 R agonist

80
Q

methyldopa

A

alpha 2 R agonist(auto R)

81
Q

methylphenidate

A

adrenergic reuptake inhibitors(for E/NE)

82
Q

tyramine

A

degraded usually by Mao-A enzyme in the gut, cheese reaction

83
Q

ephedrine

A

fascilitate release of vesicles for adrenergic

84
Q

phentolamine

A

non selective alpha R antagonist

85
Q

prazosin

A

selective alpha R antagonist(sin)

86
Q

doxazosin

A

selective alpha R antagonist

87
Q

tamsulosin

A

selective alpha R antagonist

88
Q

urapidil

A

selective alpha R antagonist, beta 1 antagonist, alpha weak agonist

89
Q

carvedilol

A

beta 1 and alpha 1 antagonist

90
Q

propanolol

A

non selective beta 1 R antagonist

91
Q

timolol

A

non selective beta 1 R antagonist

92
Q

pindolol

A

non selective beta 1 R antagonist

93
Q

sotalol

A

non selective beta 1 R antagonist

94
Q

metoprolol

A

selective beta 1 R antagonist

95
Q

bisoprolol

A

selective beta 1 R antagonist

96
Q

nebivolol

A

selective beta 1 R antagonist

97
Q

esmolol

A

selective beta 1 R antagonist

98
Q

atracurium

A

NMJ blockers

99
Q

mivacurium

A

NMJ blockers

100
Q

rocuronium

A

NMJ blockers
CURE the NMJ!!

101
Q

pipecuronium

A

NMJ blockers
‘CURE’the NMJ

102
Q

succinylcholine

A

acetylcholine R agonist

103
Q

diazepam

A

GABA-A agonist, BDZ

104
Q

baclofen

A

GABA B agonist

105
Q

tizanidine

A

alpha 2 agonist(achetylcholine R)

tiz=tizer=auto=alpha 2 R agonist
also a spasmolytic agents with diazepam, baclofen, tolperisone

106
Q

tolperisone

A

spasmolytic agents acting centrally

107
Q

dantrolene

A

Ryanodine R antagonist(direct acting mm relaxants)

108
Q

botulinum toxin

A

inhibiting release of vesicle of Ach(inhibits SNARE fusion)

109
Q

benzocaine

A

ester local anesthetics(surface acting)

110
Q

cocaine

A

ester local anesthetics(surface acting)

111
Q

lidocaine

A

amide local anesthetics(short act)

112
Q

articaine

A

amide local anesthetics(short act)
block Na channel for local anesthetics

113
Q

bupivacaine

A

amide local anesthetics(long act)
‘kind’ local anesthetics→block Na2+ channel

114
Q

levobupivacaine

A

amide local anesthetics(long act)

115
Q

morphine

A

natural opiate

116
Q

codein

A

natural opiate

117
Q

buprenorphine

A

mixed agonist of my and kappa, semisynthetic(mu agonist, kappa antagonist)

118
Q

nalbuphine

A

mixed agonist of my and kappa, semisynthetic(mu antagonist, kappa agonist)

119
Q

hydromorphone

A

strong mu agonist, semi synthetic

120
Q

dihydrocodeine

A

weak mu agonist, semisynthetic

121
Q

oxycodone

A

strong mu agonist, semi synthetic

122
Q

naloxone

A

semisynthetic antagonists of opioid R

123
Q

naltrexone

A

semisynthetic antagonists of opioid R

124
Q

N-methyl naltrexone

A

semisynthetic antagonists of opioid R

125
Q

meperidine

A

strong mu agonist, synthetic

126
Q

methadone

A

strong mu agonist, synthetic

127
Q

fentanyl

A

strong mu agonist, synthetic

128
Q

tramadol

A

synthetic weak mu agonist

129
Q

diphenoxylate

A

synthetic weak mu agonist

130
Q

loperamide

A

synthetic weak mu agonist

131
Q

colchicine

A

microtubule assembly inh for gout

132
Q

allopurinol

A

prodrug activated by xanthine oxidase, xanthine oxidase inhibitor for gout

133
Q

rasburicase

A

STIMULATE uricase enzyme to convert uric acid into allantoin in animals

134
Q

naproxen

A

NSAID cox1 inh

135
Q

ibuprofen

A

NSAID cox1 inh

136
Q

ketoprofen

A

NSAID cox1 inh

137
Q

indomethacin

A

NSAID cox1 inh

138
Q

diclofenac

A

non selective COX inhibitor

139
Q

phenylbutazone

140
Q

metamizole

141
Q

meloxicam

A

NSAID COX2 inh

142
Q

celecoxib

A

NSAID COX2 inh(selective)

143
Q

cinnarizine

A

calcium channel blocker and antihistamine for migraine

144
Q

verapamil

A

L type Ca2+ blocker for cluster headache

145
Q

sumatriptan

A

5HT 1B/1D agonist

146
Q

propanolol

A

beta blocker for migraine

147
Q

valproate

148
Q

galacanezumab

A

monoclonal Ab to treat and prevent migraines with or without aura, inhibits CN5 from firing and sending pain info to the brain

149
Q

nitrous oxide N2O

A

inhaled anesthetic(rapid onset)

150
Q

desflurane

A

inhaled anesthetic

151
Q

isoflurane

A

inhaled anesthetic

152
Q

sevoflurane

A

inhaled anesthetic

153
Q

propofol

A

IV anesthetics, GABA A inh

154
Q

etomidate

A

IV anesthetics, GABA A inh

eto tom is going on a date, the closure of home is GABA-A

155
Q

ketamine

A

IV anesthetics, NMDA R blocker

156
Q

dexmedetomidine

A

IV anesthetics, alpha 2 agonist

157
Q

midazolam

A

IV anesthetics, GABA A inh

158
Q

thiopental

A

IV anesthetics, GABA A inh

159
Q

fentanyl

A

IV anesthetics, opioid mu R agonist , synthetics

160
Q

metoclopramide

A

antiemetics

161
Q

atropine

162
Q

antihistamines

A

ex promethazine

163
Q

antacids

A

ex: omeprazole for IV anesthesia

164
Q

analgesics

A

for IV anesthesia

165
Q

haloperidol

A

1st gen antipsychotics

166
Q

droperidol

A

1st gen antipsychotics
D2 R blocker (like a DOLL!!!)

167
Q

clozapine

A

2nd gen antipsychotics

168
Q

olanzapine

A

2nd gen antipsychotics

169
Q

risperidone

A

2nd gen antipsychotics

doaneeeee after olanzapine=pinpine=antipsychotics

170
Q

aripiprazole

A

2nd gen antipsychotics

171
Q

quetiapine

A

2nd gen antipsychotics

172
Q

tiapride

A

2nd gen antipsychotics

173
Q

cariprazine

A

2nd gen antipsychotics

174
Q

clomipramine

A

tricyclic antidepressant TCA

175
Q

amitriptyline

A

tricyclic antidepressant TCA
SERT=NERT

176
Q

bupropion

A

unicyclic antidepressant

177
Q

maprotiline

A

tetracyclic antidepressant

178
Q

moclobemide

A

MAO-A inh (reversible) for antidepressant

179
Q

selegiline

A

MAO B inhibitor(reversibile) for antidepressant

180
Q

fluoxetine

A

SSRI antidepressant

181
Q

citalopram

A

SSRI antidepressant

182
Q

sertraline

A

SSRI antidepressant

183
Q

venlafaxine

A

SNRI antidepressants

184
Q

duloxetine

A

SNRI antidepressants

185
Q

reboxetine

A

SNRI antidepressants(selective NET inhibitor)

186
Q

vortioxetin

A

SSRI for antidepression

187
Q

mirtazapine

A

NE reuptake inhibitor

188
Q

agomelatine

A

melatonin(MT1, and 2) R agonist
for sleeping problems

189
Q

tianeptine

A

indirect alteration of AMPA and NMDA R activity for major depressive disorder or anxiety

190
Q

trazodone

A

5HT reuptake inh

191
Q

lithium

A

inhibits recycling of inositol, antimania

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