PH and Buffers Flashcards
1
Q
Blood ph
A
7.35-7.45
2
Q
Living range
A
7.0-7.8
3
Q
Sources of body acids
A
- Food
- Protein breakdown
- Incomplete oxidation of glucose
- Loading/unloading co2
4
Q
How’s PH regulated
A
Kidneys
Lungs
Buffer systems
5
Q
%age of water in baby/old/male/female
A
Baby: 73%
Old: 45%
Male: 60%
Female: 40%
6
Q
Henderson-hasselbach equation
A
PH=pKa + lg(a-/ha)
7
Q
PKa of COOH
A
2.34
8
Q
PKa of NH3
A
9.66
9
Q
Why is hemoglobin a good buffer
A
Many histidine residues
PKa of His=6 -> within physiological range
10
Q
Pka of oxyhaemoglobin/deoxyhemoglobin
A
Oxy= 6.8 Deoxy= 7.8
