pH Flashcards
0
Q
how is the acid-base balance regulated in the body?
A
short term by lungs (breathing out CO2).
long term by kidneys.
1
Q
where so acids in body come from?
A
protein breakdown (sulphuric acids)
incomplete glucose or fat oxidation
CO2 loading & transport in BLOOD.
2
Q
give two physiologically important buffers.
A
H2CO3 –> HCO3- (pKa 6.1)
H2PO4- –> HPO4 2- (pKa 6.8).
3
Q
what groups are important in amino acids acting as buffers and which aren’t?
A
R groups. alpha carboxyl (2.3) alpha amino (9.6)
4
Q
why is Hb a good buffer?
A
histidine residues.
