PGA, PLA, PLGA, PCL

Question 1

Structure of PGA and PLA

Answer 1

Linear

Question 2

Processing of PGA and PLA

Answer 2

Thermoplastic

Question 3

The molecular arrangement of PGA

Answer 3

Highly Crystalline

Question 4

Is PLA hydrophilic or hydrophobic?

Answer 4

Hydrophobic

Question 5

Types of PLA molecules based on chirality

Answer 5

D-PLA
L-PLA
D, L-PLA (Racemic)

Question 6

Molecular Arrangement of D-PLA and L-PLA

Answer 6

Semicrystalline

Question 7

Applications of D-PLA and L-PLA

Answer 7

High mechanical strength and toughness applications
Sutures
Orthopaedic applications

Question 8

Molecular arrangement of D,L-PLA

Answer 8

Amorphous

Question 9

Applications of D, L-PLA

Answer 9

Drug Delivery

Question 10

Applications for PGA

Answer 10

Absorbable Sutures
Dexon
mechanically weak
degrade within 2-4 weeks

Question 11

What is PLGA?

Answer 11

Copolymer between PGA and PLA

Question 12

How did PLGA affect suture applications of degradable sutures

Answer 12

More stable sutures

Question 13

Relationship between PGA, PLA, and Degradation time

Answer 13

Copolymerization of PGA with PLA reduces crystallinity, increasing the rate of hydrolysis
PLGA degrades quicker than both materials

Question 14

Molecular Arrangement of PCL

Answer 14

Semicrystalline

Question 15

Glass transition state of PCL

Answer 15

Low glass transition temperature
-60 degrees celcius

Question 16

Soluability of PCL

Answer 16

High Soluability

Question 17

Melting point of PCL

Answer 17

Low melting point
60*celcius

Question 18

The degradation rate of PCL

Answer 18

Slower than PLA, Longer lasting implant