Pestana- 13. Organ Transplantation Flashcards
1
Q
What is the only absolute contraindication to organ donation?
A
HIV
2
Q
When does hyperacute rejection present?
A
within minutes of re-establishing blood supply
3
Q
What is hyperacute rejection?
A
vascular thrombosis
4
Q
How do you prevent hyperacute rejection?
A
ABO matching
Lymphocytotoxic crossmatch
5
Q
When does acute rejection occur?
A
between 5 days and 3 months after surgery
6
Q
What signs suggest acute rejection?
A
organ dysfunction
7
Q
What is the first line of therapy for acute rejection?
A
steroid boluses
8
Q
What drugs are included with current maintenance protocols?
A
tacrolimus
mycophenolate mofetil
+/- prednisone
