Persistent Postural Perceptual Dizziness (3PD) Flashcards

1
Q

FND Spectrum of disorders

A
  • Functional movement disorders (FMD)
  • Complex regional pain syndrome (CRPS)
  • Persistent postural perceptual dizziness (3PD)
  • Functional seizures
  • Functional cognitive disorders
  • Persistent post-concussion symptoms (PPCS)
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2
Q

What is 3PD

A
  • Falls under the chronic vestibular syndrome
  • High predisposing to those who have anxiety or panic disorder
  • Precipitants: psychological distress, vestibular, other medical
  • Comorbidity: anxiety, phobia, depression
  • Predisposing factors: neurotic temperament, preexisting anxiety
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3
Q

Pathophysiologic processes in the development of PPPD

A
  • Precipitants: vestibular crisis, medical event, acute anxiety
  • Acute adaptation: visual-somatosensory dependence, high-risk postural control strategies, environmental vigilance
  • Recovery: neurologic, medical, behavioral
  • Failure of re-adaptation: provoking factors include -> upright posture, motion of self (active/passive), visual stimuli (complex/moving)
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4
Q

Diagnostic criteria for 3PD

A
  • Duration: 3 months
  • Provoking factors: exposures to complex visual motion demands or environments, active/passive head motion w/o directional preponderance, postural relationship (most severe when walking/standing)
  • Primary Sx: vague dizziness or non spinning vertigo “walking on ice”, vague unsteadiness
  • Tempo: persistent, prolonged (h
  • Examination: normal physical exam, normal vestibular testing, normal MRI
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5
Q

Main clinical characteristics of 3PD

A
  • Persisting subjective non-rotational vertigo or dizziness
  • Hypersensitivity to motion stimuli: pt’s own movement or motion of objects in the visual surround
  • Difficulties with precision visual tasks
  • Typically have normal values in clinical balance tests
  • Some pts may develop 2ndy functional gait disorder with slow or hesitant gait or “walking on ice”
  • Objective tests to prove the diagnosis of 3PD do NOT exist
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6
Q

Describe visual discomfort for 3PD patients

A
  • Those with 3PD report higher visual discomfort to images that deviate from natural spectra (busy images)
  • Images that produce high discomfort tend to share similarities with the types of challenging, highly cluttered environments that trigger 3PD symptoms
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7
Q

What is the visual vertigo analogue scale

A
  • Patient rates how severe their symptoms are for each stimuli
  • Used to help decide treatment plan/strategy
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8
Q

Outcomes for 3PD to guide treatment

A
  • Visual vertigo analogue scale
  • Situational vertigo questionnaire
  • Patient specific functional scale + fear avoidance
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9
Q

Slide 14

A
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10
Q

Slide 15

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11
Q

Presentation of symptoms for 3PD

A
  • Typically pts don’t experience symptom-free intervals but rather transition from acute to chronic symptoms
  • For episodic pts 3PD symptoms may remit & then return with recurrences of the triggering condition before settling into a persistent pattern
  • 3PD often follows an acute vestibular disorder: ~3/4 of individuals w/ longstanding 3PD have co-existing anxiety or depressive symptoms
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12
Q

Common clinical exam findings for 3PD

A
  • Normal but symptomatic oculomotor testing
  • Head impulse & postural vestibular testing normal but symptomatic
  • Abnormal & usually severe motion sensitivity
  • Overall integrity of postural control w/ weight shifts, single leg, & tandem balance, unless showing some co-morbid functional overlay
  • Presence of safety behaviors: frequent touching walls, avoidance of unsupported standing/walking
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13
Q

Red flags that are NOT 3PD

A
  • Indistinct onset (possible but not common): early in the course of progressive neurotologic disease, generalized anxiety disorder & dyautonomias may present this way
  • Progressive symptoms (slowly worsening over years): neurodegenerative disorder, peripheral neuropathy, progressive vestibular loss, cerebellar degeneration, Parkinson’s disease
  • Falls (gait disturbance is not part of 3PD): peripheral/central neurotologic disorder, cardiovascular/autonomic disorder, functional gait disorder
  • Constant symptoms (regardless or provocative factors): often with other physical complaints, somatic symptom disorder
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14
Q

Treatment options for 3PD

A
  • Medications from the classes of selective serotonin reuptake inhibitors (SSRIs) and serotonin norepinephrine reuptake inhibitors (SNRIs)
  • Habituation exercise: chronic hypersensitivity to motion stimuli & visual complexity that are core symptoms of 3PD indicate the need for a habituation/desensitization approach
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15
Q

Habituation for 3PD

A
  • Carried out in a graded fashion to motions that increase symptoms
  • here motions may be head/body motions or movement of objects in the environment
  • The effect of habituation tends to be specific to the motion executed so exercises are specific to motions that aggravate symptoms
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16
Q

Habituation versus compensation for 3PD

A
  • Habituation exercises are more appropriate for 3PD than compensation exercises
  • Most individuals with 3PD do NOT have vestibular deficits
  • Majority of those w/laboratory abnormalities show adequate compensation for deficits in basic oculomotor & postural control reflexes despite their ongoing Sx
  • X1/X2 viewing exercises may be appropriate for pts whose Sx are triggered by rapid head movements (HABITUATION)
17
Q

Treatment recommendations for 3PD

A
  • Give pts the diagnostic name & explain that it is well-known, common & potentially treatable cause of chronic dizziness
  • Vestibular rehab: to desensitize the vestibular & balance system
  • Medications: may alter the tone of interactions among vestibular, visual, & threat systems in the brain
  • Psychological therapy: cognitive behavioral ‘reprogramming’ to reduce heightened vigilance about dizziness & lessen worry/demoralization about its consequences
  • TEAM APPROACH
18
Q

Outcome measure for anxiety

A
  • Generalized Anxiety Disorder (GAD-7) Item Scale
  • Cutoff of ≥10 for identifying generalized anxiety disorder
  • 0-5 = mild
  • 6-10 = moderate
  • 11-15 = moderately severe anxiety
  • 15-21 = severe anxiety
19
Q

What is the dizziness handicap inventory

A
  • Measurement of psychiatric symptoms
  • Items include: bc of your problem are you depressed?, bc of your problem are you afraid to leave your home w/o having someone accompany you?, bc of your problem are you afraid to stay home alone?
20
Q

Describe the “Vicious Cycle” of anxiety and dizziness

A
  • Dizziness, vertigo, imbalance
  • Stress/perception of danger
  • Anxiety, hyper vigilance, panic
  • Dizziness, vertigo, imbalance
21
Q

Describe negative affectivity

A
  • Strong relationship between:
  • Negative affect
  • Catastrophizing
  • Dizziness handicap
22
Q

What can be used to demonstrate potential reversibility to the patient’s secondary functional gait disorder

A
  • Temporary improvements of standing or walking during distraction on examination