Peritonitis Flashcards
Peritonitis?
Inflammation of the peritoneal membrane
Etiology of peritonitis?
- Bacteria (esp. E coli)
- Chemicals (eg. bile, gastric acid entering the body cavity)
- Pelvic Inflammatory disease
- Iatrogenic (colonoscopy/endoscopy perforates the bowel tissue)
Pelvic Inflammatory Disease?
occurs in women when bacteria migrate up the reproductive tract and into the Fallopian tubes, move out the infundibulum and into the body cavity
What are 2 disadvantages of the peritoneum being a large structure?
- It is richly vascularized so bacteria can get into the bloodstream and spread very easily.
- Toxins produced by bacteria are rapidly absorbed
Patho behind peritonitis.
Initially, an agent (eg. bacteria) impacts the peritoneum, and then inflammation is triggered. With inflammation comes the production of purulent exudate that is THICK, STICKY, and FIBRINOUS. The nervous system brings about ileus.
What are 2 advantages of purulent exudate in peritonitis?
- It seals or plugs the perforation so that less or no content leaks out of the hole of the gut.
- it contains fluid, proteins, defense cells, and bacteria. Because it as a thick consistency, it will spread throughout the body cavity more slowly, limiting the spread of the agent/bacteria and localizing the inflammation.
Ileus?
Cessation of peristalsis
The nervous system brings about ileus. What kind of mechanism is this?
Compensatory mechanism by the sympathetic nervous system that limits GI motility and reduces the spread of bowel content through the perforation in the gut.
Manifestations of peritonitis?
- severe
- fluid shift into the bowel and abdominal cavity
- with inflammation, there is vasodilation and hyperemia
- perfusion is altered and blood is shunted (moved from one place to another) to the site of inflammation
- pain
- vomiting
- dyspnea
What does inflammation result in (in peritonitis)?
There is vasodilation and hyperemia, so CHP in the abundant vessels of the peritoneum is increased. This results in fluid moving out into the body cavity, which can result in ascites.
Why does dyspnea occur in peritonitis?
Breathing irritates the inflamed peritoneum when the diaphragm pushes on it, so the pt will minimize their depth of respirations.
Treatment options for peritonitis.
- Patient will be NPO
- IV antibiotics
- NG suction
- Fluid and electrolyte balance closely monitored
- anti-inflammatories
- analgesics
- surgery if indicated
Why will a patient be NPO?
- they will likely require surgery
2. food will initiate peristalsis, which will push more gut content out
Why is an NG suction used for treatment?
To ensure nothing is in the gut