Peripheral Vascular Pathology--Witrack Flashcards
What disease often causes iron overload?
hemochromatosis
Etiology of hemochromatosis
HFE mutation
hepcidin gene
Complications of iron overload
cardiomyopathy ± conduction disturbance, cirrhosis/hepatoma, diabetes, arthritis, skin darkening (“bronze diabetes”)
How does amylid look under congo red?
apple green bioforingence
Doxorubicin causes what type of cardiomyopathy?
dilated
Amyloidosis is associated with this neoplasm
multiple myeloma
Biggest cause of mycarditis in:
developed world
developing world
developed world: viral
developing world: Chaga’s disease
Heart transplant rejection results in this disease of the heart
myocarditis
(it’s immune-mediated)
Classic case of mycarditis
child, post-viral illness
Tx of myocarditis
steroids
What are the two major causes of hematemesis?
ruptured esophageal varices
gastric/duodenal ulcer
What does pericarditis look like on the EKG?
ST-elevations on multiple leads
Recurrent pericarditis can cause this complication
restrictive cardiomyopathy
scarring around the outside of the heart
Most common cause of cardiac tampanode
ruptured retrograde aortic aneursym
Tx of recurrent pericarditis
pericardial window
sclerosising agents
2 types of cardiac tumors
rhabdomyomas
(primary in children)
myxoma
(primarily in adults)
Rhabdomyoma
1˚ cardiac tumor
tuberous sclerosis association
children
Myxoma
connective tissue tumor of heart
usually vegetation in left atrium
may cause emboli
adults
Most common source of emboli
heart
When do you have to worry about a DVT not being related to age or having an inciting event?
< 50 y/o
no inciting event
look for hypercoagulable state
congenital defects
metastatic disease
This disease has a “string of beads” appearance on CT angio and can cause 2˚ HTN
fibromuscular dysplasia
