Peripheral Ulcerative Keratitis Flashcards
1
Q
What are the typical symptoms of PUK?
A
Pain
Photophobia
Red eye
**May be asymptomatic
2
Q
What are the signs of PUK?
A
Peripheral thinning
May have sterile infiltrate
3
Q
PUK is associated with what 5 systemic conditions?
A
Rheumatoid arthritis Wegener granulomatosis Relapsing polychondritis Polyarteritis nodosa Systemic lupus erythematosus *others
4
Q
What is the Tx for PUK?
A
Abx ung - erythromycin Q2H
Cycloplegic - Atropine 1% BID or scopolamin 0.25% BID
*consider doxycycline 100mg BID for MMP inhibition
Systemic steroid - Prednisone 60-100mg (according to response)
H2 blocker - ranitidine 150mg BID
5
Q
What class of antibiotic is erythromycin?
A
Macrolide