Peripheral neuropathies Flashcards

1
Q

What is the distribution of peripheral neuropathy?

A

Glove and stocking

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2
Q

What are the causes of peripheral neuropathy?

A

ABCDE
A - alcohol
B - B12/folate deficiency
C - chronic renal failure
D - Diabetes, drugs
E - everything else - vasculitis, paraneoplastic

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3
Q

What nerve does cubital tunnel syndrome affect?

A

Ulnar nerve

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4
Q

Where does cubital tunnel syndrome affect?

A

Medial one and a half digits

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5
Q

How does alcohol contribute to peripheral neuropathy?

A

Causes thiamine deficiency

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6
Q

Which medication for TB may cause a peripheral neuropathy?

A

Isoniazid

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7
Q

Why does isoniazid cause a peripheral neuropathy?

A

It causes a B6 deficiency

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8
Q

What nerve causes carpal tunnel syndrome?

A

Median nerve

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9
Q

Where in the hand does the palmar branch of the median nerve supply?

A

Thumb
Index and middle finger
Lateral half of the ring finger

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10
Q

Which thenar muscles does the median nerve supply?

A

Abductor pollicis brevis
Opponens pollicis
Flexor pollicis brevis

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11
Q

What are the risk factors for carpal tunnel syndrome?

A

Obesity
Repetitive movements
Diabetes
Perimenopause
Rheumatoid arthritis
Hypothyroidism
Acromegaly
Trauma

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12
Q

What is the presentation of carpal tunnel syndrome?

A

Numbness
Paraesthesia
Burning sensation
Pain

Weakness of thumb movements
Weakness of grip strength
Difficulty with fine movements
Wasting of thenar muscles

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13
Q

What is Phalen’s test?

A

Fully flexing the wrists and holding them in this position - elicits numbness and paraesthesia in the median nerve distribution

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14
Q

What is Tinnel’s test?

A

Tapping the wrist at the location where the median nerve passes through the carpal tunnel - elicits numbness and paraesthesia in the median nerve distribution

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15
Q

What is the management of carpal tunnel syndrome?

A

Rest and altered activities
Wrist splints
Steroid injections
Carpal tunnel release surgery

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16
Q

What type of injury causes a common peroneal nerve palsy?

A

Injury at the neck of the fibula

17
Q

What is the most common presentation of a common peroneal nerve lesion?

A

Foot drop

18
Q

What are the other presentations of a common peroneal nerve lesion?

A

Weak dorsiflexion
Weak eversion of the foot
Weakness of extensor hallucis longis
Sensory loss over the dorsum of the foot

19
Q

What drugs commonly cause peripheral neuropathies?

A

Amiodarone
Isoniazid
Vincristine
Nitrofurantoin
Metronidazole

20
Q

What are the other causes of foot drop?

A

L5 radiculopathy
Sciatic nerve lesion
Superficial or deep peroneal nerve lesion

21
Q

What symptoms does radial nerve damage cause?

A

Wrist drop
Sensory loss across the dorsal aspect of the 1st and 2nd metacarpals