Misc Flashcards
What is a surgical third nerve palsy?
A third nerve palsy with a fixed and dilated pupil
What is a medical third nerve palsy?
A third nerve palsy that is pupil sparing
What are the symptoms of a third nerve palsy?
Ptosis
Down and out eye
What is the most common cause of a surgical third nerve palsy?
Posterior communicating artery aneurysm
What is Lambert-Eaton syndrome?
Autoimmune condition characterised by antibodies against the pre-synaptic voltage gated calcium channels
What conditions are associated with Lambert-Eton syndrome?
Small cell lung cancer
Other autoimmune diseases
What is myotonic dystrophy?
A trinucleotide repeat disorder affecting muscle-specific chloride channels
What is the inheritance of myotonic dystrohpy?
Autosomal dominant
What are the features of myotonic dystrophy?
Patient presents in their 20s
Frontal balding
Distal wasting and weakness
Slow relaxing grip
Dysarthria
What is NMO?
Neuromyelitis optica
What is the triad of NMO?
Optic neuritis
Transverse myelitis
Positive NMO-IgG - an antibody that targets aquaporin 4
Which damaged nerve can lead to foot drop?
Common peroneal nerve
What is Cushing’s triad?
Labile breathing
Bradycardia
Hypertension
What are the most common causes of peripheral neuropathy?
ABCDE
- Alcohol
- B12/folate
- Chronic renal failure
- Diabetes
- Everything else - vasculitis, paraneoplastic
What is the distribution of peripheral neuropathy?
Glove and stocking