Peripheral Nerve Injuries Flashcards
anatomy of nerve
-Motor nerve- efferent, ventral
Sensory nerve- afferent, dorsal
Autonomic nerve- control vasodilation, sweat, non voluntary components
*the amount of nerve fibers depends on the function of the nerve depends on if a motor, sensory, or mixed nerve (size of the nerve also gives us a clue (ulnar nerve is smaller than median nerve(.
Motor nerve fibers
- originate from the ventral horn of the spinal cord and terminate at motor end plate located in the muscle.
Sensory nerve fibers
-originate from the dorsal root ganglia and terminate as free nerve endings
peripheral nerve anatomy
axons- are the small tiny dots located within the nerve. (can measure up to 3 ft or more in length)
Peripheral nerve- actually bundles of bundles of axons
Fascicles- one of the bundle of axons within a peripheral nerve.
Epineurium
- outermost layer of a nerve
- Cushions from external pressure and allows movement.
Perineurium
-Connective tissue that make up the wall of the fascicles (bundles).
Endoneurium
-surrounds individual nerve fibers/supports and protects the individual axons.
Surgical intervention-
-microvascular surgery to line up fascicles.
Mesoneurium
=slick loose connective tissue
-facilitates gliding
*peripheral nerves require extraordinary mobility in relation to surrounding tissues, sometimes sliding up to 2 centimeters as we move. This is because nerves are long (they are made up of the longest cells in our body) and often cross joints some distance from the axis of motion.
what makes a nerve happy
- space
- movement
- limited sustained tension
- good blood flow
- lots of oxygen (20% of all that we breathe)
- good nutrition
- stimulation
movement and nerve health
- improves blood flow
- facilitates gliding of fascicles and nerves
- Facilitates axoplasmic transport
- movement prevents “wrinkling” of axons within the endoneurium
- if they stay in one position they fold up on themselves and cannot glide freely
myelin sheath
- schwan cells produce myelin sheath and wrap around axon
- nodes of ranvier aids in fast conduction
unhappy nerves
- nerves do not like to be held in stretch for prolonged periods of time
- overstretch can cause traction injuries
- Compression- resting arm on end of desk while typing or resting on steering wheel.
effects of prolonged compression and stretch
- Blood flow to the nerve comes to a complete standstill at 50-70 mm Hg of pressure or more than 15.7% stretch of the nerve.
- at 8% elongation the blood flow begins to stop.
vibration
- nerves are sensitive to vibration. a little is good but too much causes damage.
- recommend people that experience a lot of vibration with job to wear shock absorbing gloves or have handles that absorb the vibration.
Dysfunction of peripheral nerves
Sensory changes
- decreased
- absent
- Abnormal sensation (allodynia, ectopic foci)
Autonomic changes
- loss of sweating or an increase in the amount of sweating
- loss of “shunting” from superficial capillaries
- other (if cast is too tight, body may increase hair growth but the hair will go away)
- want to work on desensitization right away so that they don’t develop a pain syndrome
Dysfunction of peripheral nerves
Motor changes
- Paresis
- Paralysis
- If denervation (atrophy of denervation, fibrillations)
various types of nerve injuries
- Avulsion- nerves will pull away from insertion site or the spinal cord at the root.
- Laceration- partial or complete cut of nerve fibers
- Compression- can also be caused by ganglions (tumors or osteocytes)
- Crush injury
- Edema or ischemia- cause compression and inhibit gliding
- Traction
- Radiation
- Chemotherapy
Classification of Neuropathies
- Mononeuropathy (one, carpal tunnel)
- Multiple mononeuropathy (several, CTs and cubital, also known as double crush. means there are two different things going on.
-Polyneuropathy (many, diabetic) stocking and glove
(symmetric involvement of sensory, motor, and autonomic axons)
How severe
- Myelinopathy
- Traumatic Myelinopathy (modality gated and ligand-gated channels may appear in membrane)
Traumatic Axonopathy-
Neurotmesis- severance (complete cut)
Myelinopathy
- axon is preserved- axon is fine
- no Wallerian degeneration- deterioration past point of injury
- local demylenation
- local conduction block
- full recovery expected
- my arm’s asleep
- tingling numbness
- crossing legs in a movie theatre
Stage 1- Neuropraxia (mild injury)
-Pathology (nerve intact, conduction impaired)
Recovery
- reversible
- excellent prognosis
- may not have Tinel sign (only if myelin is disrupted)
- Sensory loss present, but minimal
Therapy implications
- Short term, focused
- Good response to conservative treatment
Stage 2- Axonopathy
- interruption of axons/myelin sheath
- Wallerian degeneration- below injury is degeneration
- Good prognosis- as long as fascicle is intact (because it has a path to travel and can meet its connecting part)
- Healing through axonal sprouting guided by the neural tube.
*injury goes into the axons- interruption in the axons carrying the impulses.
Recovery
- 1” a month
- prognosis good
Therapy implications
- education (avoid what causes problem)
- moderate intervention (education, tendon and nerve glides, splinting, etc.)
- Maintain good PROM
- Follow protocols if post-op- can create tunnel so the axon knows where to go- for lacerations
Stage 3- Neurotmesis
- Loss of axon and endoneurial tube continuity. nerve completely severed.
- Most sever type of nerve injury. May require surgical intervention
- In surgery they check to see if they can get firing of the muscle tissue at the end plate for motor nerves. If the muscle doesn’t fire the prognosis is worsened. Muscles atrophy and develop fatty striations and fibrosis.
Pathology
- nerve completely severed
- spontaneous recovery impossible
- Wallerian degeneration
Recovery
- See the loss of sensory, motor and sympathetic function
- prognosis better for sensory return than motor
Therapy implications
- Long term, comprehensive care-
- a lot of training and re-education (tendon may have used to flex the thumb and now it has to extend it.
- have to have medical intervention.
- usually requires surgery.
Axon regeneration
- muscles typically begin to atrophy at 3 months post injury/compression
- irreversible muscle fibrosis occurs by 24 months
- there is an 18 day delay before nerve conduction will produce a contraction, after re-establishing the neuromuscular junction.
- 5 more days for functional reflexes.
Thoracic Outlet Syndrome
- Often misdiagnosed as carpal tunnel and cubital tunnel.
- Involved the brachial plexus- comes out of C5-T1
- If you have tight scalenes it can put compression on the brachial plexus. Results in tingling, numbness, weakness, pain.
- Sometimes there is a problem with the first rib- sometimes the ribs get hung up and stay up and we have to help them stay down in the right position.
Pec minor can be problematic- fibers run up and down- need to elevate and retract shoulders to properly stretch without stretching the brachial plexus.
*posture is super important (breast implants are a huge issue for thoracic outlet syndrome.
- can have ulnar symptoms
- posterior dislocated sternoclavicular joint is life threatening because of all the crucial structures located behind it.
Correct posture
- use caution with stretches
- progressive stretching is best
- improve forward rounded posture
- improve pelvic alignment
- Strengthen abdominal muscles
- Foam roller or towel between the shoulder blades while lying supine on floor.