Peripheral Artery Disease Flashcards
Définition
narrowing or blockage of the peripheral arteries (virtually always lower) causing ischemia.
Causes
vasculitis
buerger’s disease
atherosclerosis ( common )
Main arteries affected
aorto-illiac arteries
intrainguinal arteries.
Incidence in men and women
7% of middle aged men and 4.5% of middle aged women.
Prognosis
good prognosis but patients usually die of myocardial infarction complications or stroke.
Etiology
• Smoking
• Diabetes
• Age
• Hypertension
• Infection
• Obesity
Parhogenesis
Narrowing of artery -> decreased blood flow -> ischemia -> release of NO -> vessel damage -> claudication
Spectrum of symptoms of PAD
Asymptomatic
Pain
Ache
Tiredness
Tightness
Rest pain, poor wound healing , impending or overt gangrene when severe
Clinical features
• Intermittent claudification
Ischemic muscle pain usually felt in the calf Typically pain con
• Critical limb ischemia
Rest pain requiring opiate analgesia
Gangrene present for 2 weeks
Presence of ankle BP less than 50mmHg
• Acute limb ischemia
Paralysis and paresthesia
Pain on squeezing calf
Symptom
Pan
Pallor
Pulselessn
Perishing
• Atheroembolism -> Blue fingers
Paraesthes
Paralyses
• Subclavian steal
Dizziness
Cortical blindness
6 Ps in PAD
Pain
Paresthesia
 Incidence
20% of individuals 55 to 75 years
Most common symptom of the PAD
Intermittent claudication
Percentage of patients that’s progress to a point where amputation or revascularization are required
1 to 2%
Cause of death in PAD
Myocardial infarction
stroke
Percentage of patients with PAD that have diabetes
5 to 10%