Perioperative Management Flashcards

1
Q

Why is smoking history important pre-op?

A

When was their last cigarette? It constricts the airways and makes them hyper-reactive so they may go into bronchospasm more easily
Also heavy smokers may not know they have COPD so take care giving O2 to wake them up

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2
Q

What are the main aspects of physical examination pre-op?

A

Airway assessment
CVS
Respiratory

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3
Q

What is ASA grade 1?

A

Normal healthy patient

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4
Q

What is ASA grade II?

A

Patient with mild systemic disease and no functional limitations

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5
Q

What is ASA grade III?

A

Moderate to severe disease that results in some functional limitations

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6
Q

What is ASA Grade IV?

A

Severe systemic disease that is a constant threat to life and functionally incapactitating

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7
Q

What is ASA grade V?

A

Moribund patient not expected to survive 24 hours with or without the surgery

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8
Q

What does E after ASA grade mean?

A

That the procedure is an emergency

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9
Q

What investigations are performed routinely at pre-assessment?

A
Urinalysis
ECG if >50y
FBC
Blood glucose in diabetics
Pregnancy test for all females of reproductive age
U&Es if >60y
Coagulation, group&save
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10
Q

What are the time limits in NBM?

A

Clear fluids up to 2 hours before procedure

Light meal 6 hours before

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11
Q

What does -plasty mean at the end of a surgical procedure?

A

Surgical refashioning to regain good function

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12
Q

What does -stomy mean?

A

Artificial Union between a conduit and another conduit/the outside world

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13
Q

What is a cyst?

A

Fluid-filled cavity lined by epi/endothelium

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14
Q

What is colic?

A

Intermittent pain from over-contraction or obstruction of a hollow viscus

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15
Q

What is a sinus?

A

Blind-ending tract

Typically lined by epithelial or granulation tissue, which opens to an epithelial surface

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16
Q

What is an ulcer?

A

Interruption in the continuity of an epi/endothelial surface

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17
Q

What are the aims of preoperative assessment?

A

Know planned procedure
Improve any comorbidities which may increase risk of an adverse outcome
Anticipate potential problems
Informed consent
Appropriate prophylactic measures and premedication
Trusting patient-doctor relationship

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18
Q

What surgical presentations can warfarin cause?

A

Rectus sheath haematoma
Intraperitoneal bleeding
Retroperitoneal haematoma

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19
Q

What are the main causes of acute pancreatitis?

A

Gallstones

Alcohol

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20
Q

What drugs can cause diarrhoea?

A
Beta blockers
ACE inhibitors
Statins
Antibiotics
Metformin
Iron
Laxatives
Mefenamic acid
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21
Q

What drugs can cause constipation?

A
Antimuscarinics
Opiates
Iron
Laxatives (chronic)
Aluminium-containing antacids
Mebeverine
Gaviscon
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22
Q

How long before surgery should clopidogrel be stopped?

A

7 days before

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23
Q

How long before surgery should aspirin be stopped?

A

DO NOT STOP

Cardio and cerebroprotective benefits outweigh slight increased bleeding risk

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24
Q

How should statins be managed perioperatively?

A

Don’t stop

Reduce periop mortality

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25
Q

How should beta blockers be manage perioperatively?

A

Don’t stop

Risk of rebound angina/infarction when stopped suddenly

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26
Q

How should oral hypoglycaemics be managed perioperatively?

A

Stop from day of surgery

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27
Q

How should the OCP be managed perioperatively?

A

Stop at least 4 weeks before surgery (give alternative contraceptive advice)
Restart 2 weeks after surgery

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28
Q

How should HRT be managed periop?

A

Stop at least 4 weeks before surgery

Restart 2 weeks post-op

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29
Q

How should steroid be managed periop?

A

DO NOT STOP

Can lead to Addisonian crisis

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30
Q

When should warfarin be stopped before surgery?

A

AF: 5 days
Prosthetic heart valve: 5 days, keep INR 2-3 using heparin
Previous DVT/PE: 5 days, high-dose prophylactic LMWH

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31
Q

How do you immediately reverse warfarin?

A

Beriplex - synthetic factors 2, 7, 9 and 10

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32
Q

How else can you reverse warfarin?

A

IV vitamin K (1-5 mg slowly)

Takes 3hrs

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33
Q

How can you check for postoperative ileus?

A

Ask the patient if they have passed wind

If yes, then the colon is working and hence everything else is too

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34
Q

Which patients should have prophylactic LMWH?

A

All patients over 20 having abdominal surgery

Patients having neck surgery should not

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35
Q

What dose of dalteparin is used for VTE prophylaxis?

A

2,500 or 5,000 for high-risk patients

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36
Q

What antibiotics are used for prophylaxis of wound infection?

A

Ceftriaxone + metronidazole

Or augmentin

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37
Q

What is the treatment for opiate OD?

A

Naloxone 0.4mg IV

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38
Q

What are the steps involved in reversing anaesthetic?

A

Wellbeing (pain and PONV) then C B A…
CVS stable
Breathing for themselves
Airway (&O2)

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39
Q

Name a muscle relaxant commonly used in anaesthesia

A

Atracurium

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40
Q

Why might atropine be given in laparoscopic surgery?

A

Vagal nerve stimulation can cause bradycardia

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41
Q

Why is increased pressure needed to ventilate patients during laparoscopic surgery?

A

Abdomen is inflated, making it harder for the diaphragm to move down

42
Q

How are CO2 levels managed during surgery?

A

If pCO2 rises during op, increase rate of ventilation

High pCO2 at the end is good as it stimulates the patient to start self-ventilating

43
Q

What are the potential respiratory complications post-op?

A

Hypo ventilation

Hypoxia

44
Q

What can cause hypo ventilation postop?

A

Upper airway obstruction - decreased muscle tone, secretions, sleep apnoea
Laryngeal obstruction
Opioids causing respiratory depression

45
Q

What can cause hypoxia postop?

A

Hypo ventilation
Ventilation perfusion mismatch eg PE
Pain
Using too much O2 eg shivering

46
Q

Why should patients only be delivered to the ward once they have a normal temperature?

A

Shivering increases O2 demand
Hypothermia reduces enzyme activity in clotting
Heat needed for wound healing

47
Q

What can cause postop hypotension?

A

Drugs
Epidurals
Volume loss

48
Q

What is the main cause of postop hypertension?

A

Pain

49
Q

What are the risk factors for PONV?

A
Motion sickness
Gynae surgery
Previous PONV
Child
Female
Anxiety
50
Q

What are the anaesthetic causes of PONV?

A

Opioids
Gases
Pain
Not enough fluid

51
Q

What are the 5 parameters measured in EWS?

A
Heart rate
Resp rate
Temperature
BP
CNS (AVPU)
52
Q

What is the most important parameter in EWS?

A

Resp rate. Indicates hypoxia, hypercapnia and metabolic acidosis (DKA, sepsis, lactic acidosis)

53
Q

How should you give oxygen to a COPD patient?

A

Venturi mask

54
Q

What concentration of oxygen do nasal cannulae deliver?

A

24-35%

55
Q

Define pain

A

An unpleasant emotional and sensory experience resulting from a stimulus causing, or likely to cause, tissue damage

56
Q

What are the effects of pain?

A

Tachycardia, hypotension
Inability to deep breathe or cough
Nausea and poor appetite
Poor mobility
Stress response - sodium and water retention, oedema
Poor sleep, depression, illness behaviour, inability to work

57
Q

What is the pain pathway?

A
Stimulus
Dorsal horn of spinal cord
Modulation in Rexed laminae
Ascending pathways
Modulation by brain
Descending pathways
Effector site reflexes
58
Q

What does neuropathic pain feel like?

A

Burning

59
Q

What is step 1 in the WHO pain ladder?

A

Non-opioids eg aspirin, NSAIDs or paracetamol

60
Q

What is step 2 on the WHO pain ladder?

A

Mild opioids eg codeine, with or without non-opioids

61
Q

What is step 3 on the WHO pain ladder?

A

Strong opioids eg morphine, with or without non-opioids

62
Q

How does paracetamol work?

A

Inhibits CNS prostaglandin synthesis and blocks bradykinin-sensitive chemoreceptors peripherally

63
Q

What is the adult dose of paracetamol?

A

1g every 4-6hrs

64
Q

How do NSAIDs work?

A

COX inhibition to reduce synthesis of peripherally-acting inflammatory mediators of pain

65
Q

What does COX-1 do?

A

Constitutive production of inflammatory mediators eg GI, renal

66
Q

What are the side effects of NSAIDs?

A

GI: peptic ulcers, erosions and GI haemorrhage
Renal: can reduce renal blood flow
Resp: bronchospasm
Bleeding: anti-platelet effect
Cardiac: fluid retention and cardiac failure in borderline patients

67
Q

What is the relationship between codeine and morphine?

A

10% of codeine is metabolised to morphine

Side-effect profile may be similar

68
Q

What is the adult dose of codeine?

A

30-60mg hourly

69
Q

Give 3 examples of strong opioids

A

Morphine
Pethidine
Fentanyl

70
Q

How does morphine work?

A

Acts on M and K opioid receptors in brain and spinal cord

Reduce membrane excitability to nociceptive impulses

71
Q

What are the side effects of morphine?

A
Respiratory depression
Reduced response to hypoxia and hypercapnia
Anti-tussive (stops coughing)
Nausea, vomiting, constipation
Urinary retention
Drowsiness
72
Q

What is the adults dose of morphine?

A

0.1-0.2 mg/kg

73
Q

What is PCA?

A

Patient controlled analgesia
Pump programmed to deliver a bolus dose of drug when the patient operates a hand set
Dose is 1mg with a lock-out of 5 mins

74
Q

Where is an epidural put?

A
Epidural space (potential space)
Space in which nerves run to join the cord
75
Q

Where is spinal analgesia inserted?

A

Into the CSF

Blocks fibres at the cord level

76
Q

What is entonox?

A

Gaseous mixture of 50% O2 and 50% nitrous oxide

77
Q

Why may hospital patients be malnourished?

A
Increased nutritional requirements
Increased losses eg stoma
Decreased intake eg dysphagia
Treatment effects (nausea, diarrhoea)
Enforced starvation
Missing meals
Difficulty feeding
Unappetising food
78
Q

What is the best form of nutrition?

A

Enteral - through GI tract

79
Q

When should parenteral nutrition be considered?

A

If the patient will become malnourished without it

Eg small bowel Crohn’s when food not being absorbed

80
Q

How is TPN given?

A

Central venous line or PICC line

81
Q

What are the potential complications of TPN?

A

Sepsis from central line insertion

Thrombosis in central vein may lead to PE

82
Q

What are the 3 indications for IV fluids?

A

Maintenance
Resuscitation of pre-existing deficit
Replacement of ongoing losses

83
Q

What proportion of bodily fluid is extracellular?

A

1/3

84
Q

What proportion of body fluid is intravascular?

A

1/15

85
Q

What is the minimum urine output that is considered adequate?

A

0.5ml/kg/hr

86
Q

Why are even small changes in plasma potassium bad?

A

Potassium is mainly intracellular

There may be large changes before plasma levels change

87
Q

Why do IV fluids need to be isotonic with plasma?

A

If hypotonic - red cell haemolysis

If hypertonic - red cell crenation

88
Q

Name 3 crystalloid fluids

A

Normal saline
Dextrose
Hartmann’s

89
Q

Name 4 colloid solutions

A

Volpex
Starch
Albumin
Blood products

90
Q

What does 1 litre of 0.9% normal saline contain?

A

154mmol Na+

154mmol Cl-

91
Q

What does 1 litre of Hartmann’s contain?

A

131mmol Na+
5mmol K+
111mmol Cl-

92
Q

What is the maximum safe rate to deliver IV potassium?

A

5mmol/hr

93
Q

What proportion of 5% dextrose solution remains in plasma?

A

1/15

Glucose taken up rapidly by cells, so solution acts just like water

94
Q

What proportion of 0.9% saline remains in plasma?

A

1/5

95
Q

What proportion of colloid solutions stays in plasma and why?

A

All of it
Contains proteins, which can’t cross the capillary membrane. Their osmotic effect means all the water remains in plasma too

96
Q

What are the maintenance requirements of sodium for adults?

A

2mmol/kg/24h

97
Q

What are the maintenance requirements of water for adults?

A

40ml/kg/24h

98
Q

What are the potassium requirements for adults?

A

1 mmol/kg/24h

99
Q

When may fluid replacement be required?

A

Vomiting
Diarrhoea
High output stoma
Enterocutaneous fistula

100
Q

What ions is diarrhoea rich in?

A

K+ and HCO3-

101
Q

What ions is vomit rich in?

A

K+, H+ and Cl-

102
Q

How do you assess a patient’s fluid status?

A
Peripheral perfusion
Pulse rate, blood pressure
JVP
Flow-based measurements
Urine output