Perioperative Flashcards
What pre-op checks must you do on every patient?
OP CHECS
- Operative fitness (cardioresp)
- Pills
- Consent
- History (MI, asthma, HTN, jaundice, anaesthetic complications, DVT, anaphylaxis)
- Ease of intubation: neck arthritis, dentures, loose teeth
- Clexane
- Site (correct and marked)
How should you manage HRT/OCP prescribing perioperatively?
Stop 4 weeks before a major surgery/leg surgery
Restart 2 weeks post op if mobile
What blood tests should you do preoperatively?
- FBC
- U+E
- G+S
- clotting
- glucose
- Plus:
- LFTs if liver disease, EtOH, jaundice
- TFTs if thyroid disease
- Se electrophoresis if west indies, med, africa
- Cross match
- 4 units for gastrectomy
- 6 units for AAA
How long should patients be NBM for before an op?
≥2h clear fluids, ≥6h solids
What kinds of bowel preps are there?
- Stimulant e.g. picolax: picosulfate and magnesium citrate
- Osmotic e.g. Klean Prep: macrogol
What are the risks of bowel preps?
- Liquid bowel contents spilled during surgery
- Electrolyte disturbance
- Dehydration
- Increased rate of post op anaestomotic leak
When should you give antibiotic prophylaxis?
GI surgery (20% post op infection if elective) and djoint replacement; give it 15-60 mins before surgery
What prophylactic antibiotics do you give for biliary surgery?
Cef 1.5g + metronidazole 500mg IV
What prophylactic antibiotics do you give for CR or appendicectomy surgery?
Cef + met TDS
What prophylactic antibiotics do you give for vascular surgery?
co amoxiclav 1.2g IV TDS
What prophylactic antibiotics do you give for MRSA positive patients before surgery?
vancomycin
How do you manage DVT risk in surgical patients?
- Low risk: early mobilisation
- Medium risk: early mobilisation + TEDS + 20mg enoxaparin
- High risk: early mobilisation + TEDS + 40mg enoxaparin + intermittent compression boots perioperatively
- Start prophylaxis at 1800 post op
- May continue medical prophylaxis at home up to 1 month
What are the ASA grades?
- Normally healthy
- Mild systemic disease
- Severe systemic disease which limits activity
- Systemic disease which is a constant threat to life
- Moribund: not expected to survive 24h even with operation
How do you manage a permanent pacemaker/ICD in surgery?
Can be reset/triggered by diathermy. Change pacemaker to fixed pace and switch off ICD + attach external defibrillator pads
Why is diabetes a surgical risk?
- Surgery increases stress hormones which antagonise insulin
- NBM
- Increased risk of infection and poor wound healing
- IHD and PVD common
How do you generally manage IDDM patients in surgery?
- Put them first on the list and inform surgeon and anaesthetist
- May use GKI infusion
- Sliding scale may not be needed for minor ops; consult diabetic specialist nurse
- ±stop long acting insulin night before
- Omit AM insulin if morning surgery
- Start sliding scale
- 5% dex with 20mmol KCl 125ml/hr
- Infusion pump with 50u actrapid
- Check CPG hourly and adjust insulin
- Check glucose hourly aiming for 7-11mM
- Post op
- continue sliding scale until eating
- Switch to SC regimen around a meal
How do you manage NIDDM patients in surgery?
- If glucose control poor (fasting >10mM) treat as IDDM
- Omit oral hypoglycaemics on morning of surgery
- Eating post op: resume oral hypoglycaemics with meal
- Not eating post op:
- Check fasting glucose on morning of surgery
- Start insulin sliding scale
- Consult specialist team re: restarting PO treatment
How do you manage diet controlled diabetics in surgery?
Usually not a problem; they might be briefly insulin dependent post op so monitor CPG
Why do steroids increase postop risk?
Reduced neutrophil and fibroblast function
What are the risks of steroid usage perioperatively?
- Poor wound healing including anastomotic leak
- Infection
- Adrenal crisis (Addison’s)
How do you manage steroid prescribing perioperatively?
- If you can wean the dose pre op, do
- Need to increase steroid to cope with stress
- Consider cover if high dose steroids within last year
- Major surgery: hydrocortisone 50-100mg IV with pre med then 6-8 hourly for 3 days (until back on oral steroids)
- Minor: as for major but hydrocortisone only for 24h
What are the risks of operating on jaundiced patients?
- Obstructive jaundice: increased risk of post op renal failure
- Coagulopathy
- Increased infection risk may cause cholangitis
How do you manage jaundiced patients preoperatively?
- Avoid morphine in pre med
- Check clotting and consider pre op vit K
- Give 1L NS pre op (unless CCF) -> moderate diuresis
- Urinary catheter to monitor output
- Prophylaxis: cef and met
How do you manage jaundiced patients intraoperatively?
Hourly urine output monitoring and NS titrated to output
How do you manage jaundiced patients postoperatively?
Intensive monitoring of fluid status and consider CVP + frusemide if poor output despite NS
How do you classify surgical risk in liver disease?
Child’s Classification of Surgical Risk in Hepatic Dysfunction (graded A-C)
How do you generally manage anticoagulated patients perioperatively?
- Very minor surgery can be done without stopping warfarin if INR <3.5
- Avoid epidural, spinal, regional blocks if anticoagulated
- In general continue aspirin/clopidogrel unless high risk of bleeding then stop 7d before surgery
How do you manage low risk anticoagulated patients e.g. AF?
Stop warfarin 5d pre op; need INR <1.5 and restart next day
How do you manage high risk anticoagulated patients perioperatively e.g. valves, recurrent VTE?
- Need bridging with LMWH
- Stop warfarin 5d pre op and start LMWH
- Stop LMWH 12-18h pre op and restart 6h post op
- Restart warfarin next day
- Stop LMWH when INR >2
How do you manage anticoagulated patients needing emergency surgery?
- Discontinue warfarin
- Vit K 0.5mg slow IV
- Request FFP or PCC to cover surgery
What are the perioperative risks with COPD/smoking?
- Basal atelectasis
- Aspiration
- Chest infection
What are the 3 main aims of anaesthesia?
Hypnosis, analgesia, muscle relaxant
What would be the drugs used in a typical anaesthetic regimen?
- Induction: IV propofol
- Muscle relaxation: either -
- Depolarising: suxamethonium
- Non-depolarising: vecuronium, atracurium
- Airway: ET tube, LMA
- Maintenance: usually a volatile agent added to N2O/O2 mix e.g. halothane, enflurane
- End of anaesthesia: change inspired gas to 100% O2, reverse paralysis with neostigmine and atropine (prevent muscarinic side effects)
What drugs are included in operative pre medication?
- 7 As
- Anxiolytics and amnesia e.g. temazepam
- Analgesics e.g. opioids, paracetamol, NSAIDs
- Anti emetics e.g. odansetron 4mg/metoclopramide 10mg
- Antacids e.g. lansoprazole
- Anti-sialogue e.g. glycopyrolate (decreases secretions)
- Antibiotics
What agent might you use for regional anaesthesia and why would you use regional over general?
Bupivicaine (long acting). Use for minor procedures, unsuitable for GA
What are some contraindications to nerve or spinal blocks?
Local infection or clotting abnormality
What are some potential complications of anaesthesia?
- Propofol induction - cardiorespiratory depression
- Intubation
- Oropharyngeal injury with laryngoscope
- Oesophageal intubation
- Loss of pain sensation
- Urinary retention
- Pressure necrosis
- Nerve palsies
- Loss of muscle power
- Corneal abrasion
- No cough -> atelectasis and pneumonia
- Malignant hyperpyrexia from halothane or suxamethonium
- Anaphylaxis
What is malignant hyperpyrexia, what causes it and how do you treat it?
- Rare complication precipitated by halothane or suxamethonium
- AD inheritance
- Rapid rise in temperature and masseter spasm
- Treat with dantrolene and cooling
What are some common anaesthetic triggers for anaphylaxis?
Antibiotics, colloid, NM blockers like vecuronium
Why are analgesics necessary in surgery?
- Humanitarian
- Autonomic activation causes arteriolar constriction, decreased wound perfusion and therefore poor healing
- Patients might not mobilise leading to VTE and decreased function
- Decreased respiratory excursion and cough can cause atelectasis and pneumonia
What drugs are commonly given as a PCA?
Morphine, fentanyl
What drug is commonly given through an epidural?
Bupivicaine
Describe the analgesic ladder for post op pain relief
- Non opioid ± adjuvants
- Paracetamol
- NSAIDS:
- Ibuprofen 400mg/6h PO max
- Diclofenac 50mg PO/75mgIM
- Weak opioid + non opioid ± adjuvants; add:
- Codeine
- Tramadol
- Dihydrocodeine
- Strong opioid + non opioid ± adjuvants; add:
- Morphine: 5-10mg/2h max
- Oxycodone
- Fentanyl
What are the 2 main cautions when using spinal/epidural anaesthesia?
Respiratory depression and neurogenic shock causing hypotension
What are the aims of ERAS?
- Opimise pre op preparation
- Avoid iatrogenic problems like ileus
- Minimis adverse physiological/immunological responses to surgery
- Raised cortisol and low insulin (absolute or relative_
- Hypercoagulability
- Immunosuppression
- Increase speed of recovery and expedite return to function
- Recognise abnormal recovery and allow early intervention
What are the pre-op components of ERAS?
- Aggressive physical optimisation (hydration, BP, anaemia, DM, comorbidities)
- Smoking cessation ≥4 weeks before op
- Admission on day of surgery
- Avoid prolonged fast
- Carb loading prior to surgery e.g. carb drinks to reduce early catabolic response
- Fully informed patient encouraged to participate in recovery
- Avoid opiates and epidurals (GIT effects, early mobilisation)
What are the intra op components of ERAS?
- Short acting anaesthetic agents
- Epidurals
- Minimally invasive techniques
- Avoid drains and NGTs where possible
What are the post op components of ERAS?
- Aggressive treatment of pain and nausea
- Early mobilisation and physio
- Early resumption of oral intake including carb drinks from 6h
- Early discontinuation of IV fluids
- Remove drains and urinary catheters ASAP