Perio Studies

Question 1

Best, 1990

Answer 1

• reliability of attachment loss levels in a longitudinal clinical trial
• conclusion: it’s very hard to get exact agreement (happens only 44% of time!)
• this is the VCU study

Question 2

Vanooteghem, 1990

Answer 2

• wanted to know if you can predict sites that would get worse over time
• used the “gold standard” person
• 60 sites (7%) with an initial PD of 4mm+ progressed
• they OVER estimated the number of sites they thought would get worse
• results showed it’s very challenging for us to identify which surface of a tooth is going to get worse

Question 3

positive predictive value

Answer 3

the proportion of sites identified by the expert clinician that actually lost the attachment

Question 4

sensitivity

Answer 4

the proportion of sites with attachment loss that were identified

Question 5

AA

Answer 5

motile
aggressive perio
may invade tissue
may be transmissible within families

Question 6

tannerella forsythia

Answer 6

non-motile

enzymes can destroy immunoglobulins and factors of the complement system

Question 7

Grossi, 1994

Answer 7

risk factors study for AL

(4): age 45+, moderate to heavy smoker, diabetic, and B. forsythus/tannerrella forsythia present

Question 8

less risk of gingivitis

Answer 8

allergy (Grossi)
being single (Moss)

Question 9

Genco, 1996

Answer 9

compared post menopausal women with and without HRT

conclusion: there is a protective effect of estrogen on the periodontium but it is negated by smoking

Question 10

Payne, 1997

Answer 10

estrogen and alveolar bone density
conclusion: there is decreased bone density in non-smoking females/no HRT
in smokers, HRT made no difference

Question 11

Moss, 1996

Answer 11

effects of stress on periodontitis - 
financial stress (4.0)
depression increased odds ratios of other stresses

–being single was protective (0.68)