perio disease: epidemiology and risk factors Flashcards
epidemiology
the study of the distribution and determinants of health-related states or events in specified populations and the application of this study to control health problems
3 main purposes of epidemiology
- determine amount/distribution of disease in a population
- investigate disease casualty
- control the disease
whats the difference between public health and clinical practice in terms of perio disease?
health of group vs health in individuals
-determinants of disease: dental plaque in individuals vs low SES or access to preventative dentistry
what is the underlying assumption in epidemiology?
distribution of disease among members of a population is not random
prevalence
proportion of cases within a population at a given point in time
**proportion not rate
=# of cases present in population/persons at risk for dises
*estimates burden of disease in a given population
why is prevalence useful?
for estimating health care resource needs
what is prevalence influenced by?
population dynamics and additive/cumulative effect of aging
what results in higher prevalences?
more sensitive diagnostic tests and new treatment modalities that enhance survival
incidence
average percentage of unaffected persons who will develop the disease of interest during a given period of time
*(risk or probability that a person will become a case…it IS rate
=# of NEW cases in population/persons in pop at risk
observation studies
cross sectional
cohort
case/control
(retrospective mostly)
manipulation studies
community intervention trials
randomized clinical trials
what leads to causality exploration?
case/control cohort
what leads to causality determination?
clinical trial
retrospective cohort
exposure–> outcome
case control
exposure
RCT and prospective cohorts
exposure–>outcome
retrospective measures at —
end
prospective measures at —
beginning
experimental study
preventions and treatments for diseases, active manipulation
observational study
causes, preventions, and treatments for diseases, passively
what increases the probability of making the correct diagnosis?
diagnostic tests
sensitivity
probability of a positive test among persons with disease
specificity
probability of a negative test among persons without the disease
positive predictive value
probability that a person has the disease given that a positive test has been obtained
negative predictive value
probability that a person does not have disease given that a negative test has been obtained
sens/spec is the probability of what?
a test result
predictive values are probability of what?
disease status
risk
predicts the ‘‘who will get the disease” in a specific period of time