Pericarditis, pleural effusion, tamponade Flashcards

1
Q

Acute pericarditis is associated with _ and _ on ECG

A

Acute pericarditis is associated with diffuse ST elevation and PR-interval depression on ECG

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2
Q

Viral infection is a common cause of pericarditis; _ is a classic example

A

Viral infection is a common cause of pericarditis; Coxsackie B virus is a classic example

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3
Q

Upon cardiac auscultation, patients with acute pericarditis will commonly have a _ described as a _

A

Upon cardiac auscultation, patients with acute pericarditis will commonly have a pericardial friction rub described as a high-pitched scratchy sound

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4
Q

The pericardial fluid is located between _ and _ layer of the heart

A

The pericardial fluid is located between parietal layer of the serous pericardium and visceral layer of the serous pericardium

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5
Q

The layers of the pericardium include _ and _

A

The layers of the pericardium include visceral pericardium and parietal pericardium
* The visceral layer is attached to the heart surface and may include adipose tissue
* The parietal layer is the outer layer

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6
Q

Between the parietal and visceral pericardium is the _

A

Between the parietal and visceral pericardium is the pericardial cavity/space
* Normally we find 15-50 mL of serous fluid inside

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7
Q

The pericardial fluid gets produced by _

A

The pericardial fluid gets produced by lining epithelial cells

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8
Q

Name some causes of acute pericarditis

A

Acute pericarditis may be caused by
* Infections
* Toxin/ metabolites (uremia in kidney disease)
* Systemic disease (RA, sarcoidosis, SLE, etc)
* Postinjury (MI, radiation)
* Tumor, aortic dissection, etc

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9
Q

Clinical manifestations of acute pericarditis include _

A

Clinical manifestations of acute pericarditis include..
* Fever, malaise, myalgia
* Chest pain- pleuritic (worse with inspiration/cough)
* Chest pain that is worse in supine position, better sitting up and forward
* Non-productive cough
* Dyspnea

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10
Q

The ECG marker for acute pericarditis is _

A

The ECG marker for acute pericarditis is diffuse ST elevation with PR depression
* The diffuse ST elevation represents inflammation of the myocardium
* The PR depression is abnormal atrial repolarization from the inflammation

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11
Q

Acute pericarditis sounds like _

A

Acute pericarditis sounds like friction rub best heard over the LSB
* It is highly specific
* Sounds like rubbing a balloon

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12
Q

Patients with pericardial effusion may have pulsus paradoxus which is _

A

Patients with pericardial effusion may have pulsus paradoxus which is a fall of systolic BP > 10 during inspriation
* Normally we get increased venous return and preload during inspiration that should increase SV and BP
* But when the pericardium is full of fluid, the increase in RV volume compresses the LV such that SV is reduced and BP dips

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13
Q

The difference between pericadial effusion and cardiac tamponade is that _

A

The difference between pericadial effusion and cardiac tamponade is that the pericadial constraint is present throughout the cardiac cycle with cardiac tamponade

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14
Q

Cardiac tampanode is _

A

Cardiac tampanode is an accumulation of pericardial fluid under pressure
* Compresses all chambers
* Greatly enhances ventricular interdependence
* Diastolic pressure in each chamber increases and equalizes

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15
Q

Becks triad of cardiac tamponade

A

Beck’s triad:
1. Elevated JVP
2. Muffled heart sounds
3. Hypotension

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16
Q

Explain what the atrial waveform would look like in cardiac tamponade

A

Impaired RV filling –> blunted y-descent

Increased right sided venous return –> impaired RV filling due to high pericardial pressure –> septum bulges into LV cavity –> impaired LV filling –> impaired cardiac output (shock)

17
Q

Name three acute causes of cardiac tamponade

A

Acute causes of cardiac tamponade:
1. Trauma
2. Cardiac or aortic rupture
3. Complication of invasive procedure

18
Q

Name the subacute causes of cardiac tamponade

A

Name the subacute causes of cardiac tamponade:
* Neoplastic
* Uremic
* Idiopathic
* Post-viral

19
Q

Constrictive pericarditis occurs after _ causes _

A

Constrictive pericarditis occurs after chronic inflammation of the pericardium causes calcification of the pericardial sac
* This inhibits the transmission of thoracic pressure into the pericardial space
* Limits the expansion of the ventricles (lowers compliance)

20
Q

During constrictive pericarditis, the heart needs to really suck in its blood early during diastole; explain

A

During constrictive pericarditis, the heart needs to really suck in its blood early during diastole –> compression of the heart does not occur until the cardiac volume approximates the volume of the pericardium –> there is rapid early diastolic filling

21
Q

How does compression differ in cardiac tamponade vs. constrictive pericarditis?

A

The compression experienced in cardiac tamponade lasts the entire cycle

The compression experienced in constrictive pericarditis is only during mid-to-late diastole (think of a rubber band)

22
Q

Describe what the jugular vein waveform would look like in constrictive pericarditis

A

Early diastolic filling is characteristic of constrictive pericarditis; therefore the y descent will have a dramatic descent (atria emptying into ventricles)

23
Q

A jugular venous waveform that shows a shallow y descent is likely (tamponade/ constrictive pericarditis)

A

A jugular venous waveform that shows a shallow y descent is likely tamponade (because the atria can’t really relax)

24
Q

In a healthy individual, the JVP should _ upon inspiration

A

In a healthy individual, the JVP should collapse upon inspiration
* Drop in intrathoracic pressure –> increased venous return –> transmitted through the pericardium to the heart –> blood into the LA –> collapse of JVP

25
Q

In constrictive pericarditis, upon inspiration what happens to the JVP?

A

In constrictive pericarditis, the inspiration and drop in intrathoracic pressure is not transmitted to the heart because the pericardium is scarred –> JVP increases
* This is called Kussmal’s sign: increased JVP on inspiration

26
Q

Causes of constrictive pericarditis

A

Constrictive pericarditis is caused by:
* Idiopathic
* Viral
* Post-cardiac surgery
* Post-radiation therapy
* Post infectious
* Malignancy, trauma, sarcoidosis

27
Q

A commonly associated pathogen with constrictive pericarditis is _

A

A commonly associated pathogen with constrictive pericarditis is TB

28
Q

Constrive pericarditis can sometimes present like liver failure, why?

A

Because constrictive pericarditis causes right heart failure–> affects the liver
* Peripheral edema
* Ascites
* Fatigue
* Elevated JVP
* Hepatomegaly
* Pericardial knock (3rd heart sound)