Pericarditis Flashcards
What is the pericardium?
A fibroelastic sac containing a thin layer of fluid that surrounds the heart and the roots of the great vessels
What does the pericardium do?
Sets heart in mediastinum and limits its motion
Protects it from infections coming from other organs (such as lungs)
Prevents excessive dilation of the heart in cases of acute volume overload
Lubricates the heart
What is pericarditis?
Inflammation of the pericardium
What are the causes of acute pericarditis?
Viral infection
Bacterial infection
Fungal infection
Uraemia
Autoimmune rheumatic disease
Trauma
MI Dressler’s Syndrome
Malignancy
Which viruses are usually responsible for causing acute pericarditis?
Coxsackie B
Echovirus
HIV
Which bacteria are usually responsible for causing pericarditis?
Tuberculosis pericarditis
Pneumococcus
Which is the most common cause of acute pericarditis?
Virus
What is meant by uraemic pericarditis?
Pericarditis caused by azotaemia: abnormally high levels of nitrogen-containing compounds in the blood
BUN (blood urea nitrogen) is very much higher than the normal level
What is azotaemia?
Abnormally high levels of nitrogen containing compounds in the blood
- urea
- creatinine
What causes azotaemia?
Poor kidney perfusion
Kidney failure
What is BUN?
Blood urea nitrogen
If high indicates poor renal filtration
What are the clinical features of acute pericarditis?
Sharp retrosternal chest pain which is relieved by leaning forward
Pain may be worse on inspiration
Pain may radiate to neck or shoulders
Pericardial friction rub sound
Systemic symptoms like fever, malaise etc.
Diagnosis of acute pericarditis.
ECG: concave upwards (saddle shaped) ST segment elevation across all leads
How can you differentiate ST elevation caused by acute pericarditis from MI?
ST elevation in MI will have flatter shape and will only be in some leads
In pericarditis the elevation is concave saddle shaped and is in all leads
How long is it before acute pericarditis becomes chronic?
6 weeks