Pericardial Disease Flashcards

1
Q

Most common cause of pericarditis?

A

Idiopathic, presumed to be viral

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2
Q

Which viruses cause pericarditis?

A
Coxsackie A/B
Echovirus
Adenovirus
Influenza
HIV
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3
Q

What infections are associated with pericarditis caused by HIV?

A

TB

Histoplasmosis

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4
Q

What other causes of the for pericarditis besides viral?

A
Bacterial
Neoplastic
Radiation
Connective tissue disease
Dressler's syndrome
Uremia
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5
Q

Drugs that cause pericarditis via drug induced lupus? (3)

A

Procainamide
Isoniazid
Hydralazine

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6
Q

Fluid accumulation in pericarditis is usually what type?

A

Serous

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7
Q

Clinical features of pericarditis?

A

Chest pain
Pericardial friction rib
Electrocardiogram changes
Pericardial effusion

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8
Q

Patient’s biggest complaint that should alert you to pericarditis?

A

Chest pain unrelated to exertion

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9
Q

Patients will do what to attempt to alleviate pericardial pain?

A

Sit seated and lean forward

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10
Q

When will patient’s chest pain be the worst?

A

Deep inspiration and laying flat

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11
Q

To hear pericardial rub how do you position the patient?

A

Sit upright, lean forward

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12
Q

Where do you listen for pericardial friction rub?

A

Best heard with diaphragm of stethoscope over left sternal border

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13
Q

What will you see on chest x-ray for pericarditis?

A

Enlarged cardiac silouette

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14
Q

Electrocardiogram changes in patients with acute pericarditis signals inflammation of what?

A

Epicardium since pericardium itself is electrically inert

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15
Q

What will you see in changes on a pericarditis ECG?

A

S-T and P-R segment changes

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16
Q

ECG stage 1?

A

Diffuse ST elevation and PR depression

17
Q

ECG stage 2?

A

Normalization of ST and PR segments

18
Q

ECG stage 3?

A

Diffuse T wave inversions after ST segments have become isoelectric

19
Q

ECG stage 4?

A

Normalization of ECG or indefinite presence of T wave inversions

20
Q

Acute pericarditis complications?

A

Pericardial effusion and tamponade
Constrictive pericarditis
Relapse

21
Q

How do you treat idiopathic and viral pericarditis?

A

NSAIDS and Colchicine

22
Q

How do you treat pericarditis post MI?

A

Aspirin and Colchicine, avoid NSAIDs because they will interfere with healing and scar formation

23
Q

What metabolizes Colchicine?

A

CYP 450

24
Q

When do you use Glucocorticoids for pericarditis?

A

Acute pericarditis due to connective tissue disease
Uremic pericarditis
Patients with symptoms refractory to standard therapy

25
Q

When do you do pericardiocentesis?

A

Tamponade

Suspected purulent pericarditis

26
Q

when do you do intensified hemodialysis?

A

Uremic pericarditis

27
Q

Electrical Alterans on ECG is due to what?

A

Heart swinging around in pericardial sac

28
Q

Pericardial effusion will compress what?

A

Right art and ventricle due to less thickness

29
Q

What is pulsus paradoxus?

A

Fall of systolic blood pressure of greater than 10mmHg with inspiration

30
Q

Tamponade causes what change in the jugular venous curve?

A

Loss of the y descent

31
Q

3 ECG findings of pericardial tamponade?

A

Sinus Tachycardia
Low voltage
Electrical Alternans on ECG

32
Q

Right heart cauterization does what for those with pericardial tamponade?

A

Equalization of pressures

33
Q

Appropriate initial management of patient with pericardial tamponade?

A
IFV to increase right ventricular volume
Avoid diuretics 
Vasopressors
Pericardiocentesis
Pericardial window procedure
34
Q

Constrictive pericarditis causes what?

A

Chronic thickening/scarring of pericardium that impairs diastolic filling of LV and RV

35
Q

Effect of constrictive pericarditis on early diastole?

A

Unimpaired

36
Q

Constrictive Pericarditis etiology?

A

Idiopathic or viral

37
Q

Physical findings in Constrictive pericarditis?

A

Elevated JVP with prominent X and Y descents
Kussmaul’s sign: Increase JVP on inspiration
Pericardial knock
Systemic congestion

38
Q

Chest X-ray will show what in chronic pericarditis?

A

Calcification

39
Q

Therapy for chronic pericarditis?

A

Diuretics

Pericardial stripping