Peptidergic Regulation

Question 1

What is endocrine regulation?

Answer 1

Sensor cells secrete a hormone into the blood which acts on a distance cell

Question 2

What is paracrine regulation?

Answer 2

Sensor cells secrete a paracrine mediator into the extracellular space which act on local cells

Question 3

Gastrin: released from, stimulus and targets

Answer 3

G-cells
Neural, amino acids and peptides
ECL cells and parietal cells

Question 4

Cholecystokinin: released from, stimulus and targets

Answer 4

I-cells
Fatty acids and amino acids
Vagal afferents and pancreatic acinar cells

Question 5

Secretin: released from, stimulus and targets

Answer 5

S-cells
Acid in small intestine
Vagal afferents and pancreatic duct cells

Question 6

Motilin: released from, stimulus and targets

Answer 6

Intestinal cells
Neural
Upper GI tract

Question 7

Gastric inhibitory peptide: released from, stimulus and targets

Answer 7

K cells
Fatty acids, glucose and amino acids
Beta cells of pancreas

Question 8

Glucagon like peptide: released from, stimulus and targets

Answer 8

L cells
Carbohydrates and fatty acids
Endocrine pancreas

Question 9

What do APUD cells release?

Answer 9

Gastrin, CCK, secretin, GIP and motilin

Question 10

What doe mucus neck cells release?

Answer 10

Mucus and bicarbonate

Question 11

What do parietal cells release?

Answer 11

Gastric acid and intrinsic factor

Question 12

What do ECL cells release?

Answer 12

Histamine

Question 13

What do chief cells release?

Answer 13

Pepsinogen and gastric lipase

Question 14

What do D cells release?

Answer 14

Somatostatin

Question 15

What is the role of somatostatin?

Answer 15

Increases acid secretion and mucosal growth