peptide, sulphonamides, flouroquinolones, nitrofurans, nitromidazoles Flashcards

1
Q

Peptide AB groups

A

polypeptide antibiotics

glycopeptide antibiotics

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2
Q

polypeptide antibiotis substances

A

bacitracin
polymyxin B
polymixin E = colistin

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3
Q

polypeptide antibiotics mode and mech of action

A

concentration dependent bactericidal

act like a cationic detergent

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4
Q

glycopeptide antibiotics substances

A

vancomycine

teicoplanin

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5
Q

glycopeptide antibiotics mode and mech of action

A

time dependent bactericidal

inhibition of cell wall synthesis

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6
Q

rifamycines substance

A

rifampicin

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7
Q

rifamycines mode and mech of action

A

time dependent bactericidal

inhibit bacterial DNA-dependent RNA polymerase

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8
Q

pseudomonic acid sub

A

mupirocin

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9
Q

pseudomonic acid mode and mech of action

A

bactericidal

inhibition of cell wall synthesis

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10
Q

phosphonic acid derivates sub

A

fosfomycin

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11
Q

phosphonic acid derivates mode and mech of action

A

bactericidal

inhibition of cell wall synthesis

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12
Q

fusidic acid sib

A

fusidic acid

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13
Q

fusidic acid mode and mech of action

A

bacteriostatic

inhibition of protein synthesis

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14
Q

Sulphonamides sub

A
sulfadimidine
sulfadiazine
sulfachlorpyrazine
sulfamethoxine
sulfaquinoxaline
sulfasalazine
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15
Q

sulphonamides mode and mech of action

A

separately bacteriostatic and in combination time dependent bactericidal
inhibition of folic acid synthesis

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16
Q

Fluoroquinolones Generations

A

generation 1-4

17
Q

Fluoroquinolones Gen 1 sub

A

nalidixic acid

18
Q

fluoroquinolones Gen 2 sub

A
flumequine
norfloxacin
orbifloxacin
ciprofloxacin
enrofloxacin
danofloxacin
difoloxacin
marbofloxacin
19
Q

Fluoroquinolones Gen 3 sub

A

levofloxacin

sparfloxacin

20
Q

Fluoroquinolones Gen 4 sub

A

pradofloxacin

moxifloxacin

21
Q

Fluoroquinolones gen 1-4 mode and mech of action

A

concentration dependent bactericidal

inhibition of DNA synthesis

22
Q

nitrofurans sub

A

nitrofurantoin

furazolidone

23
Q

nitrofurans mode and mech of action

A

bactericidal

destroy the DNA of bacteria

24
Q

nitroimidazoles sub

A

matronidazole
ronidazole
tinidazole

25
Q

nitroimidazoles mode and mech of action

A

concentration dependent bactericidal

destroy the DNA of the bacteria