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Prudent use of antibiotics > Final Entry test > Flashcards

Final Entry test Flashcards

Mode and Mech of action and Substance group pairing

1
Q

Benzylpenicillin - NA, K

Benzylpenicillin - procaine

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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2
Q

Benzylpenecilin - benzathine

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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3
Q

PHenoxymethyl - penicillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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4
Q

oxacillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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5
Q

Cloxacillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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6
Q

Dicoloxacillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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7
Q

Flucloxacillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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8
Q

Amoxicillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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9
Q

Ampicillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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10
Q

Ticarcillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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11
Q

Piperacillin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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12
Q

Clavulanic acid

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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13
Q

Sulbactam

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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14
Q

Tazobactam

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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15
Q

cephazoline

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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16
Q

Cephapirin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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17
Q

Cefadroxil

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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18
Q

Cephalexin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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19
Q

Cefuroxime

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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20
Q

Ceftiofur

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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21
Q

Cefovecin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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22
Q

Ceftriaxone

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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23
Q

Cefotaxime

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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24
Q

Cefoperazone

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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25
Q

Cefquinone

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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26
Q

Imipenem

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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27
Q

Meropenem

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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28
Q

Aztreonam

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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29
Q

Tigemonam

A

Time dependent bactericidal

Inhibition of cell wall synthesis

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30
Q

Streptomycin

A

Concentration dependent bactericidal

Inhibition of protein synthesis (30s subunit), mistranslation

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31
Q

Neomycin

A

Concentration dependent bactericidal

Inhibition of protein synthesis (30s subunit), mistranslation

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32
Q

Paromomicin

A

Concentration dependent bactericidal

Inhibition of protein synthesis (30s subunit), mistranslation

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33
Q

Kanamicin

A

Concentration dependent bactericidal

Inhibition of protein synthesis (30s subunit), mistranslation

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34
Q

Gentamicin

A

Concentration dependent bactericidal

Inhibition of protein synthesis (30s subunit), mistranslation

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35
Q

Tobramycin

A

Concentration dependent bactericidal

Inhibition of protein synthesis (30s subunit), mistranslation

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36
Q

Amikacin

A

Concentration dependent bactericidal

Inhibition of protein synthesis (30s subunit), mistranslation

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37
Q

Apramycin

A

Concentration dependent bactericidal

Inhibition of protein synthesis (30s subunit), mistranslation

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38
Q

Spectinomycin

A

Bacteriostatic

Inhibition of protein synthesis (30s Subunit), mistranslation

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39
Q

Chlortetracycline

A

Bacteriostatic

Inhibition of protein synthesis (30s Subunit), mistranslation

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40
Q

Oxytetracycline

A

Bacteriostatic

Inhibition of protein synthesis (30s Subunit), mistranslation

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41
Q

tetracycline

A

Bacteriostatic

Inhibition of protein synthesis (30s Subunit), mistranslation

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42
Q

Doxycycline

A

Bacteriostatic

Inhibition of protein synthesis (30s Subunit), mistranslation

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43
Q

Minocycline

A

Bacteriostatic

Inhibition of protein synthesis (30s Subunit), mistranslation

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44
Q

Erythromycin

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

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45
Q

Azithromycin

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

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46
Q

Clarithromycin

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

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47
Q

Spiramycin

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

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48
Q

Tylosin

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

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49
Q

Tylvalosin

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

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50
Q

Tilmicosin

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

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51
Q

Tulathromycin

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

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52
Q

Gamithromycin

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

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53
Q

Tildipirosin

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

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54
Q

Lincomycin

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

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55
Q

Clindamycin

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

56
Q

Tiamulin

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

57
Q

Valnemulin

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

58
Q

Chloramphenicol

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

59
Q

Florfenicol

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

60
Q

Thiamphenicol

A

Bacteriostatic

Inhibition of protein synthesis (50s Subunit), mistranslation

61
Q

Bacitracin

A

Concentration dependent bactericidal

act like cationic detergent

62
Q

Polymyxin B

A

Concentration dependent bactericidal

act like cationic detergent

63
Q

Polymyxin E = Colistin

A

Concentration dependent bactericidal

act like cationic detergent

64
Q

Vancomycin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

65
Q

Teicoplanin

A

Time dependent bactericidal

Inhibition of cell wall synthesis

66
Q

Rifampicin

A

Time dependent bactericidal

Inhibit bacterial DNA-dependent RNA polymerase

67
Q

Mupirocin

A

Bactericidal

Inhibition of cell wall synthesis

68
Q

Fosfomycin

A

Bactericidal

Inhibition of cell wall synthesis

69
Q

Fusidic acid

A

Bacteriostatic

Inhibition of protein synthesis

70
Q

Sulfadimidine

A

Separately bacteriostatic and in combination time dependent bactericidal
Inhibition of folic acid synthesis

71
Q

Sulfadiazine

A

Separately bacteriostatic and in combination time dependent bactericidal
Inhibition of folic acid synthesis

72
Q

Sulfachlorpyrazine

A

Separately bacteriostatic and in combination time dependent bactericidal
Inhibition of folic acid synthesis

73
Q

Sulfamethoxasole

A

Separately bacteriostatic and in combination time dependent bactericidal
Inhibition of folic acid synthesis

74
Q

Sulfadoxine

A

Separately bacteriostatic and in combination time dependent bactericidal
Inhibition of folic acid synthesis

75
Q

Sulfaquinoxaline

A

Separately bacteriostatic and in combination time dependent bactericidal
Inhibition of folic acid synthesis

76
Q

Sulfasalazine

A

Separately bacteriostatic and in combination time dependent bactericidal
Inhibition of folic acid synthesis

77
Q

Trimethoprim

A

Separately bacteriostatic and in combination time dependent bactericidal
Inhibition of folic acid synthesis

78
Q

Baquiloprim

A

Separately bacteriostatic and in combination time dependent bactericidal
Inhibition of folic acid synthesis

79
Q

Nalidix acid

A

Concentration dependent bactericidal

Inhibition of DNA synthesis

80
Q

Flumequine

A

Concentration dependent bactericidal

Inhibition of DNA synthesis

81
Q

Norfloxacin

A

Concentration dependent bactericidal

Inhibition of DNA synthesis

82
Q

Orbifloxacin

A

Concentration dependent bactericidal

Inhibition of DNA synthesis

83
Q

Ciprofloxacin

A

Concentration dependent bactericidal

Inhibition of DNA synthesis

84
Q

Enrofloxacin

A

Concentration dependent bactericidal

Inhibition of DNA synthesis

85
Q

Danofloxacin

A

Concentration dependent bactericidal

Inhibition of DNA synthesis

86
Q

Difloxacin

A

Concentration dependent bactericidal

Inhibition of DNA synthesis

87
Q

Marbofloxacin

A

Concentration dependent bactericidal

Inhibition of DNA synthesis

88
Q

levofloxacin

A

Concentration dependent bactericidal

Inhibition of DNA synthesis

89
Q

Sparfloxacin

A

Concentration dependent bactericidal

Inhibition of DNA synthesis

90
Q

Pradofloxacin

A

Concentration dependent bactericidal

Inhibition of DNA synthesis

91
Q

Moxifloxacin

A

Concentration dependent bactericidal

Inhibition of DNA synthesis

92
Q

Nitrofurantoin

A

Bactericidal

Destroy the DNA of bacteria

93
Q

Furazolidone

A

Bactericidal

Destroy the DNA of bacteria

94
Q

Metronidazole

A

Concentration dependent bactericidal

Destroy the DNA of bacteria

95
Q

Ronidazole

A

Concentration dependent bactericidal

Destroy the DNA of bacteria

96
Q

Tinidazole

A

Concentration dependent bactericidal

Destroy the DNA of bacteria

97
Q

B- lactam antibiotics Main groups

A 
Penicillins
B-lactamase-inhibitors
Cephalosporins
carbapenems
monobactams
98
Q

Benzylpenicillin - Na, K
Benzylpenicillin - procaine
Benzylpenicillin - benzathine
Phenoxymethyl - penicillin

A

Narrow spectrum Penicillins
Penicillins
B-lactam antibiotics
TDBC, Inhibit cell wall synth

99
Q

Oxacillin
cloxacillin
dicloxacillin
flucloxacillin

A

Penicillinase stable Penicillins
penicillins
B-lactam antibiotics
TDBC, Inhibit cell wall synth

100
Q

Amoxacillin

ampicillin

A

Broad spectrum pencilillins
Penicillins
B-lactam antibiotics
TDBC, Inhibit cell wall synth

101
Q

ticarcillin

piperacilin

A

Penicillins acting against pseudomonas spp
penicillins
B-lactam antibiotics
TDBC, Inhibit cell wall synth

102
Q

Clavulinic acid
sulbactam
tazobactam

A

B-lactamase inhibitors
B-lactam antibiotics
TDBC, Inhibit cell wall synth

103
Q

Cephazolline
cephaprirn
cefadroxil
cephalexin

A

Gen 1 Cephalosporins
B-lactam antibiotics
TDBC, Inhibit cell wall synth

104
Q

Cefuroxime

A

Gen 2 Cephalosporins
B-lactam antibiotics
TDBC, Inhibit cell wall synth

105
Q 
Ceftiofur
Cefovecin
ceftriaxone
cefotaxime
Ceftazidime
Cefoperazone
A

Gen 3 Cephalosporins
B-actam antibiotics
TDBC, Inhibit cell wall synth

106
Q

Cefquinome

A

Gen 4 cephalosporins
B-lactam antibiotics
TDBC, Inhibit cell wall synth

107
Q

Imipenem

Meropenem

A

Carbapenems
B-lactam antibiotics
TDBC, Inhibit cell wall synth

108
Q

Azteronam

tigemonam

A

Monobactams
B-lactam antibiotics
TDBC, Inhibit cell wall synth

109
Q

Streptomycin
neomycin
paromomicin
kanamycin

A

Aminoglycosides

CDBC, Inhibit 30s

110
Q 
gentamycin
tobramycin
amikacin
aparmycin
spectinomycin
A

Aminoglycosides
CDBC, Inhibit 30s

Spectinomycin - bacteriostatic

111
Q

Chlortetracycline
Oxytetracycline
Tetracycline

A

Short acting tetracyclines

BStatic, Inhibit 30s

112
Q

Doxytetracycline

minocycline

A

Long acting tetracyclines

BStatic, Inhibit 30s

113
Q

Erythromycin

azithromycin

A

Macrolides

Bstatic, inhibit 50s

114
Q

clarithromycin
Spiramycin
Tylosin

A

Macrolides

Bstatic, inhibit 50s

115
Q

tylvalosin
tilmicosin
tulathromycin

A

Macrolides

Bstatic, inhibit 50s

116
Q

gamithromycin

tildipirosin

A

Macrolides

Bstatic, inhibit 50s

117
Q

Lincomycin

clindaymcin

A

Lincosamides

Bstatic, inhibit 50s

118
Q

Chloramphenicol
Florfenicol
Thiamphenicol

A

Phenicols

Bstatic, inhibit 50s

119
Q

Bacitracin
Polymyxin B
Colistin - Polymyxin E

A

Polypeptide antibiotics
Peptide Ab
CDBC, cationic detergent

120
Q

Vancomycin

Teicoplanin

A

Glycopeptide antibiotics
Peptide Ab
TDBC, inhibit cell wall synth

121
Q

Rifampicin

A

Rifamycines

TDBC, inhibit bact DNA-dependent RNA polymerase

122
Q

Mupirocin

A

Pseudomonic acid

BC, Inhibit cell wall synth

123
Q

Fosfomycin

A

Phosphonic acid derivates

BC, inhibit cell wall synth

124
Q

Fusidic acid

A

Fusidic acid

BStatic, inhibition of protein synthesis

125
Q

Sulfadimidine

Sulfadiazine

A

Sulphonamides
Separately Bstatic, combination TDBC
Inhibit folic acid synthesis

126
Q

Sulfadoxine
Sulfaquinoxaline
Sulfasalazine

A

Sulphonamides
Separately Bstatic, combination TDBC
Inhibit folic acid synthesis

127
Q

Sulfachlorpyridazine
Sulfachlorpyrazine
Sulfamethoxasole

A

Sulphonamides
Separately Bstatic, combination TDBC
Inhibit folic acid synthesis

128
Q

Trimethoprim

Baquiloprim

A

Diaminopyramidines
Separately Bstatic, combination TDBC
Inhibit folic acid synthesis

129
Q

Nalidixic acid

A

Gen 1 Fluoroquinolones

CDBC, Inhibition of DNA Synthesis

130
Q

Flumequine

Norfloxacin

A

Gen 2 Fluoroquinolones

CDBC, Inhibition of DNA Synthesis

131
Q

Danofloxacin
Difloxacin
Marbofloxacin

A

Gen 2 Fluoroquinolones

CDBC, Inhibition of DNA Synthesis

132
Q

Orbifloxacin
Ciprofloxacin
Enrofloxacin

A

Gen 2 Fluoroquinolones

CDBC, Inhibition of DNA Synthesis

133
Q

Levofloxacin

Sparfloxacin

A

Gen 3 Fluoroquinolones

CDBC, Inhibition of DNA Synthesis

134
Q

Pradofloxacin

Moxifloxacin

A

Gen 4 Fluoroquinolones

CDBC, Inhibition of DNA Synthesis

135
Q

Nitrofuratoin

Furazolidone

A

Nitrofurans

Bactercidal, Destroy Bact DNA

136
Q

Metronidazole
Ronidazole
Tinidazole

A

Nitroimidazoles

CDBC, Destroy Bact DNA

Prudent use of antibiotics (5 decks)

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