Pentose Phosphate Pathway Flashcards
what is the balanced equation of this pathway
3G6P + 6NADP+ + 3H2O <-> 6NADPH + 3CO2 + 2F6P + GAP
where do these reactions take place
the cytosol (liver, mammary, adrenal, adipose tissues)
what are the two stages of the pathway
oxidative and nonoxidative
what is the structure of phosphoglucanolactone
glucose with carboxyl on C1 and phosphate on C6
what does glucose 6 phosphate dehydrogenase do
substitutes a carboxyl for an OH on C1 of glucose 6 phosphate
which enzyme converts phosphoglucanolactone to 6-phosphogluconate
glucanolactonase
what is the structure of ribulose 5 phosphate
C1 CH2OH - C=O - HCOH - HCOH - CH2OPO3(2-) C5
what reducing agent is used in the oxidative stage
NADP+
what are the major products of P3
2F6P and GAP
what is ribose 5 phosphate used for
synthesis of nucleotides for RNA and DNA
how many G6P molecules are present in the P3 pathway
3
what is the cofactor for transketolase
TPP
