Penile Flashcards

1
Q

What is the difference between T1a and T1b penile cancer?

A

T1a: not HG (grade 3), no LVI and no perineural (PNI) invasion
T1b: HG, presence of LVI or PNI

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2
Q

What is Tis penile cancer?

A

Penile intraepithelial neoplasia

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3
Q

What is Bowens Disease?

A

Penile lesion on the shaft

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4
Q

What is erythoplasia of Queryat?

A

Penile lesion on the glans

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5
Q

What is T1 disease in the:

  • glans
  • foreskin
  • shaft?
A

glans: invades LP
foreskin: invades dermis, LP or dartos fascia
shaft: invades connective tissue between epidermis and corpora regardless of location

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6
Q

What is the difference between T2 and T3 disease in penile cancer?

A

T2 invades corpus spongeiosum with or without urethral invasion
T3 invades corpora cavernosa (including tunica albuginea) with or without urethral invasion

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7
Q

What are predictors of metastasis for SCC of penis?

A

grade, stage, PNI or LVI

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8
Q

How does 5FU work?

A

blocks DNA synthesis - inhibits thymidylate synthetase actiity

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9
Q

What are the boarders of an inguinal node dissection?

A

superior - Inguinal ligament
lateral - sartorious
medial - adductor longus

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10
Q

When do you do pelvic LNs if nodes are nonbulky and mobile?

A

If >3 + inguinal nodes

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11
Q

What do you do for fixed inguinal nodes?

A

Chemotherapy then PLND and bilateral inguinal LN dissection

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12
Q

When do you FNA pelvic lymph nodes?

A

If marginal size, ~1-2cm

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13
Q

What is the chemo regimen for penile cancer?

A

TIP - paclitaxel, ifosfamide, cisplatin
or
5FU + Cisplatin

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14
Q

When would you do unilateral inguinal node dissection?

A

If unilateral palpable recurrence after extended period of surveillance (>6-9mos)

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15
Q

What is Bushke lowenstein

A

Verrucous Carcinoma

No LND required

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16
Q

What is the lymph node management for non palpable low grade penile cancer?

A

observation

17
Q

What is the lymph node management for non palpable high grade penile cancer?

A

bilateral superficial inguinal lymph node

18
Q

What is the lymph node management for palpable non bulky penile cancer?

A

bilateral superficial and deep

19
Q

how is extramammary’s paget disease treated?

A

wide local excision

20
Q

what is associated w/ extramammary paget disease?

A

abdominal malignancy