Penicillins And Cephalosporins Flashcards
What is infections is penicillin G the best choice of treatment for?
Meningecoccal, pneumonococcal and strep pyogens
Which penicillin is used for the treatment of psuedomembranous colitis?
Piperacillin
What is the name of a derivative form of benzyl penicillin? And why it is better?
Pen V which has better absorption
What strain of bacteria is benzylpenicillin active against?
Gram positive (with the exception of meningococcal which is a gram negative)
How is penicillin G administered?
IV
How is pen V administered?
Orally
What strain of bacteria is flucloxacillin active against?
Gram positive and gram negative
What’s the differences between benzyl penicillin and amoxicillin?
Amoxicillin has much better oral absorption orally and has cover against gram negative bacteria
What is amoxicillin active against?
Streptococci and some coliforms
What Is co amoxiclav active against?
Streptococci and all coliforms
What infections is flucloxacillin the first choice of treatment for?
Staphylococcal (because it contains beta lactase enzyme which will make it active against beta lactamases i.e. staphylococcal bacteria such as staph aureus)
What agent is used to represent flucloxacillin in laboratory testing?
Meticillin
What bacteria is resistant to meticillin?
MRSA
What is piperacillin active against?
It is a broad spectrum antibiotic with extended gram negative cover.
(Active against positive and negative)
Also active against anaerobic species
Name 2 specific bacteria which piperacillin is active against which makes it useful and different from other penicillins
Enterococcus faecalis and psudomonas spp.
What is piperacillin used in combination with and what does this form?
Tazobium which forms tazocin
What is the street names for tazocin?
Taz / pip
What is tazobium?
Beta lactamases inhibitor
What type of anti biotic is imipenam?
Carbapenam
Why are Carbapenams good antibiotics?
They have the widest cover of all and have activity against most bacteria including anaerobes
Name a 1st generation cephalosporin.
Cipfaradine
Name a 3nd generation cephalosporin.
Ceftriaxone
Name a 2nd generation cephalosporin
Cefuroxime
