Penicillins And Cephalosporins Flashcards

1
Q

What is infections is penicillin G the best choice of treatment for?

A

Meningecoccal, pneumonococcal and strep pyogens

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2
Q

Which penicillin is used for the treatment of psuedomembranous colitis?

A

Piperacillin

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3
Q

What is the name of a derivative form of benzyl penicillin? And why it is better?

A

Pen V which has better absorption

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4
Q

What strain of bacteria is benzylpenicillin active against?

A

Gram positive (with the exception of meningococcal which is a gram negative)

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5
Q

How is penicillin G administered?

A

IV

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6
Q

How is pen V administered?

A

Orally

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7
Q

What strain of bacteria is flucloxacillin active against?

A

Gram positive and gram negative

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8
Q

What’s the differences between benzyl penicillin and amoxicillin?

A

Amoxicillin has much better oral absorption orally and has cover against gram negative bacteria

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9
Q

What is amoxicillin active against?

A

Streptococci and some coliforms

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10
Q

What Is co amoxiclav active against?

A

Streptococci and all coliforms

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11
Q

What infections is flucloxacillin the first choice of treatment for?

A

Staphylococcal (because it contains beta lactase enzyme which will make it active against beta lactamases i.e. staphylococcal bacteria such as staph aureus)

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12
Q

What agent is used to represent flucloxacillin in laboratory testing?

A

Meticillin

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13
Q

What bacteria is resistant to meticillin?

A

MRSA

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14
Q

What is piperacillin active against?

A

It is a broad spectrum antibiotic with extended gram negative cover.
(Active against positive and negative)
Also active against anaerobic species

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15
Q

Name 2 specific bacteria which piperacillin is active against which makes it useful and different from other penicillins

A

Enterococcus faecalis and psudomonas spp.

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16
Q

What is piperacillin used in combination with and what does this form?

A

Tazobium which forms tazocin

17
Q

What is the street names for tazocin?

A

Taz / pip

18
Q

What is tazobium?

A

Beta lactamases inhibitor

19
Q

What type of anti biotic is imipenam?

A

Carbapenam

20
Q

Why are Carbapenams good antibiotics?

A

They have the widest cover of all and have activity against most bacteria including anaerobes

21
Q

Name a 1st generation cephalosporin.

A

Cipfaradine

22
Q

Name a 3nd generation cephalosporin.

A

Ceftriaxone

23
Q

Name a 2nd generation cephalosporin

A

Cefuroxime