Anti-bacterial Drugs

Question 1

What type of antibiotic is teicoplanin?

Answer 1

Glycopeptide

Question 2

What type of anti biotic is daptomycin?

Answer 2

Cyclic lipopeptide

Question 3

What type of antibiotic is linezolid?

Answer 3

Oxazolidinone

Question 4

What does trimethoprim inhibit?

Answer 4

Purine synthesis (of nucleic acid synthesis)

Question 5

What is vancomycin active against?

Answer 5

Gram possitive bacteria

Question 6

What doe betalactams inhibit?

Answer 6

Cell wall synthesis
(By binding to PBP rendering it inactive which is required for peptidoglycan synthesis of cell wall)

Question 7

What strain of bacteria is gentamycin active against?

Answer 7

Gram negative

Question 8

What are macrolides useful for in some patients?

Answer 8

Alternative treatment to pencillin and cephalosporin of gram possitive infections if patient is allergic to penicillins

Question 9

About 10% of what 3 species are resistant to gentamicin?

Answer 9

Staph. Aureus, staph. pyogens and step. Pneumoniae

Question 10

What strain of bacteria is daptomycin active against?

Answer 10

Gram possitive (particularly MRSA)

Question 11

How do flouroquinolones work?

Answer 11

They inhibit DNA synthesis (of nucleic acid synthesis)

Question 12

What strain of bacteria is ciproflaxin active against?

Answer 12

Gram negative

Question 13

What is a downfall of ciproflaxin?

Answer 13

Cannot be used in children

Question 14

Name a newer flouroquinolone which also has activity against gram possitives e.g. Strep.pneumonia

Answer 14

Levoflaxin

Question 15

How does sulphamethoxazole work?

Answer 15

Inhibits Purine synthesis

Question 16

What group of drugs has the widest spectrum of all?

Answer 16

Carbapenems

Question 17

What is different about piperacillin compared to all the other penicillins?

Answer 17

Piperacillin is active against the pseudononas species

Question 18

Name 2 carbapenems.

Answer 18

Imipenem and meropenem

Question 19

Co-trimoxazole is used for the treatment of what?

Answer 19

Chest infections

Question 20

How is linezolid administered?

Answer 20

Orally

Question 21

How is gentamicin administered?

Answer 21

Intravenously

Question 22

What is trimethoprim, used on its own, used for the treatment of?

Answer 22

Urinary tract infection

Question 23

What is co-trimaxazole and what is it used for the treatment of?

Answer 23

Flouroquinolones - Trimethoprim and sulphamethoxazole
Treatment of chest infection

Question 24

Clarithromysin provides better cover against what bacteria?

Answer 24

Haemophillus influenzae

Question 25

Why has the use of cephalosporins decreased?

Answer 25

They encourage clostridium difficile infections

Question 26

Name a cephalosporin which is part of the: 1st generation 2nd generation 3rd geberation

Answer 26

1st - cephradine 2nd - cefuroxime 3rd- cephtriaxone

Question 27

The cephalosporin ceftriaxone is part of what geberation?

Answer 27

3rd

Question 28

The cephalosporin cefuroxime is part of which generation?

Answer 28

2nd

Question 29

Macrolides are also active against organisms that cause what?

Answer 29

Atypical pneumonia

Question 30

What type of antibiotic is azithromycin?

Answer 30

Macrolide

Question 31

What is azithromycin used for the treatment of?

Answer 31

Chlamydia infection (single dose)

Question 32

Name 5 miscellaneous anti biotics.

Answer 32

Metronidazole Fusidic acid Trimethoprim Tetracyclines Clindamycin

Question 33

What is the miscellaneous antibiotic tetracycline used for the treatment of?

Answer 33

Genital tract and chest infection

Question 34

What is the miscellaneous antibiotic trimethoprim used for the treatment of?

Answer 34

UTI

Question 35

When trimethoprim is attached to sulphamexazole to create co- trimoxazole, what is it used to treat?

Answer 35

Chest infection

Question 36

What is the miscellaneous antibiotic metronidazole active against? And therefore what is it used to treat?

Answer 36

All anaerobes (possitive and negative) Intra abdominal sepsis

Question 37

What is fusidic acid active against? What infections is it used to treat?

Answer 37

Streptococcal bacteria Osteomyelitis and pneumonia

Question 38

Which miscellaneous anti biotic is active against gram possitive and anaerobes?

Answer 38

Clindamycin

Question 39

Name a miscellaneous antibiotic that is only active against anaerobes.

Answer 39

Metronidazole

Question 40

Name 2 drugs which arent used in pregnancy

Answer 40

Metronidazole and trimethoprim

Question 41

Name the antibiotics that are known to be safe in pregancy

Answer 41

Penicillins, cephalosporins, nitrofurantoin ( urinary antiseptic)

Question 42

An adult admitted to the hospital with lovar penumonnia is likely to be infected with pneumoicocci. Therefore what agent should he be treated eith until the lab results are back?

Answer 42

Benzylpenicillin or amoxicillin

Question 43

What are the bacteriostatic drugs?

Answer 43

Macrolides, tetracyclines and trimethoprim