Penicillins Flashcards
1
Q
Parentral formulations of Penicillins are
A
Amphicillin
Pipercillin
Ticarcillin
2
Q
Tubular sectetion is inhibited by
A
Probenecid
3
Q
Penicillin are derivatives of
A
6 aminipenicilliac acid and beta lactam
4
Q
Which penicillin is excreted in bile
A
Nafcillin
5
Q
Which Penicillins undergoes enterohepatic cycling
A
Amphicillin
6
Q
What penicillins are administered IM
A
Procaine and benzathine
7
Q
They cross BBB
A
When meninges are inflamed
8
Q
They cross BBB
A
When meninges are inflamed
9
Q
MOA
A
Bactericidial via
- Binding to PBPs
- inhibits transpeptidation
- Activation of autolytic enzymes
10
Q
Resistance maybe due to
A
- Formation of beta lactamases
- Structural change in target PBPs
- Changes in porin structure
