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Chemotherapeutic Drugs > Anti Malarial > Flashcards

Anti Malarial Flashcards

1
Q

Blood

A 
Chloroquine 
Amodiaquine
Quinine
Pyrimethamine
Lumefantrine
Artemisinin
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2
Q

Tissue

A

Primaquine

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3
Q

Pre erythrocytic

A

Pyrimethamine
Primaquine
Proguanil

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4
Q

Gameocidal

A

Vivax: quinine
Falciparum: primaquine

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5
Q

Sporontocoides

A

Primaquine

Choroguanide

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6
Q

8-aminoquinolone

A

Primaquine

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7
Q

Gametocyte for all four plasmodia

A

Primaquine

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8
Q

AE of primaquine

A

Hemolytic anemia for G6PD Deficiency
Abdominak pain with chloroquine
Methhemoglobinemia
CI Pregnancy

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9
Q

4 aminoquinolone

A

Chloroquine

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10
Q

Mainstay of antimalarial therapy

A

Chloroquine

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11
Q

Also used for Amoebiasis

A

Chloroquine

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12
Q

AE of chloroquine

A

Rash
Headache
Blurred vision

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13
Q

Multidrug resistant falciparum

A

Mefloquine

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14
Q

AE of Mefloquine

A 
Dizziness
Confusions 
Hallucinations 
Depression
ECG abnormality with quinine
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15
Q

Interfere with heme polymerization

A

Quinine and Quinidine

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16
Q

Cinchonism

A

Quinine and Quinidine

Vomitting, vertigo, tittinus

17
Q

Severe multidrug resistant malria

A

Artemisinin

18
Q

High doses of artemisinin

A

Neurotoxicity and QT prolongation

19
Q

Dihyrdofolate reductase inhibitor (reduces tetrahydrofolate)

A

Pyrimethamine

20
Q

Prophylaxis for pregnant women

A

Sulfadoxine

Pyrimethamine

21
Q

Prevention in chloroquine resitsbt malaria

A

Doxycycline
Mefloquine
Malarone (atovaquone+proguanil)

Chemotherapeutic Drugs (4 decks)

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