PEM Flashcards
Anticholinergic poisoning
Sxs:
example drugs:
Sxs: Hot as a hare Red as a beet Dry as a bone Blind as a bat Mad as a hatter Full as a flask
example drugs: antihistamines, TCAs, atropine, scopolamine, Benztropine (used for parkinsons)
Cholinergic poisoning
Sxs:
example drugs:
Sxs: can give muscarinic and nicotinic sx
muscarinic: DUMBELLS Diarrhea, diaphoresis Urination Miosis Bradycardia Emesis Lacrimation Lethargy Salivation
nicotinic: adds muscle fasciculations and flaccid paralysis
example drugs: organophosphates, pilocarpine
Sympathomimetic poisoning
Sxs:
example drugs:
Sxs: Mydriasis Tachycardia Hypertension Hyperthermia Seizures
(to differentiate from anticholinergic, sympathomimetic has diaphoresis and increased bowel sounds)
example drugs: cocaine, amphetamines, ephedrine, PCP
Drug poisoning that causes hypotension
CRASH
Clonidine, calcium channel blockers
Rodenticides (containing arsenic, cyanide)
Antidepressants, aminophylline, antihypertensive (beta blockers)
Sedative hypnotics
Heroin or other opioids
Drugs that cause Miosis
COPS
Cholinergics, clonidine
Opiates, organophosphates
Phenothiazides (antipsychotics), pilocarpine, pontine hemorrhage
Sedative-hypnotics
Drugs that cause Mydriasis
SAW
sympathomimetics
anticholinergics
withdrawal
Antidote for TCA overdose
Sodium bicarb
Antidote for organophosphate poisoning
Atropine and pralidoxime
Antidote for beta blockers
glucagon; insulin/glucose
Antidote for calcium channel blockers
insulin/glucose
Antidote for cyanide
hydroxocobalamin
Antidote for methemoglobinemia
methylene blue
works by oxidizing NADPH which is able to convert the methemoglobin to hemoglobin so it is able to carry oxygen again
Antidote for sulfonylureas
octreotide
Antidote for iron
deferoxamine
Gases that can make you quickly pass out
Hydrogen sulfide (manure pit)
Cyanide (tx with:
1.) hydrocobalamin (b12)- converts cyanide to nontoxic form
2.)sodium nitrate (causes methemoglobin which cyanide preferentially bonds to)DONT USE IN FIRES
3.) sodium thiosulfate (converts cyanide to nontoxic form also)
bladder capacity formula
(age+2) x 30