Peds Flashcards
Explain why a child desaturates quicker
Increased O2 consumption
Slightly deceased FRC due to collapse of chest wall
Unable to maintain a negative intrathoracic pressure
Increased work of breathing due weak intercostal muscles (no slow twitch fibers)
Explain the differences of a pediatric airway
Large occiput Higher larynx More anterior airway Large tongue Omega shaped, epiglottis Smaller and fewer airways - increased airway resistance
What is different about the CV system in peds?
Stroke volume is fixed, they are heart rate dependent
They have immature SNS so less responsive to catecholamines and may have hypotension without tachycardia
Why do kids have a faster inhalational induction?
They have a higher alveolar ventilation
Decreased FRC
And higher blood flow to organs
Lower blood/tissue solubility
Why do kids require larger doses of propofol?
Larger volume of distribution
Shorter elimination half life
Increased plasma clearance
Why are babies prone to hypoglycemia?
Decreased glycogen stores
What are the kidney function differences in children versus adults?
Decreased ability to concentrate the urine –> prone to dehydration
Decreased GFR
Approaches normal around 6 months - 2 years old
What are the pharmokinetics of NMBs in neonates?
Faster onset due to shorter circulation times Large ECF (larger Vd) Unpredictable response due to immature NMJ and hepatocytes
Why wouldn’t you use succinylcholine in a child?
Risk of hyperkalemic cardiac arrest (especially if undiagnosed neuromuscular disorder)
Precipitation of MH
A peds patient is crashing and you have no access. What do you do?
IO 18 G to the tibia
You have a neonate who needs an emergency ex lap, what will you do to optimize respiratory support in the OR?
Take out HME (decrease dead space)
Don’t let peak pressures rise above 15-18
How do you manage laryngospasm in a peds patient?
100% oxygen (turn off nitro) Deepen anesthetic Jaw thrust Positive pressure at 20 cm H2O IM rocuronium Lidocaine 1-1.5 mg/kg Atropine 0.02 mg/kg IM for hypoxia induced bradycardia 100 Mcg/kg epi down tube
Patient has a barking cough in PACU, what are you concern about? How do you manage? What could you do to prevent this.
Post-extubation croup from glottic or tracheal edema
Racemic epinephrine
0.5mg/kg of dexamethasone
A peds case is getting a circumcision, how much volume do you give in the caudal?
0.5 ml/kg or 1.25 mg/kg
Neonates comes in with a volvulus, what’s your anesthetic plan?
Pass OG/NG before induction
RSI with rocuronium and ketamine for induction
Judicious opioid use (fentanyl 1 Mcg/kg) for pain control, use ketamine as well
Maintenance with sevoflurane
NG tube after induction
Fluid resuscitation- 6 ml/kg/hr
What are the anesthetic considerations of a congenital diaphragmatic hernia?
Pulmonary hypertension
Pulmonary hypoplasia
Increased airway reactivity and resistance
Intestinal malrotation - aspiration, dehydration
Hypotension due to IVC compression after repair
Contralateral PTX
Other associated defects: ASD, coarctation, ToF, VSD, hydrocephalus
What is your anesthetic plan for congenital diaphragmatic hernia?
Start sedation with precedex, give glycopyrrolate as antisialoge, will also help against hypoxia induced bradycardia. Use ketamine to maintain pressure and airway reflexes.
Place NGT
Preoxygenation
Awake intubation sitting up - need to avoid PPV due to risk of barotrauma, contralateral PTX, gastric distention.
Induce : RSI
Keep spontaneously breathing on sevoflurane thru case
Maintain PaO2 between 90-100%
Allow permissive hypercapnea
Keep peak pressures less than 30, PIP < 25
How much fluid do you resuscitate with for third space losses in a big surgery?
6-10 ml/kg/hr
What is the anesthetic plan for TE fistula?
Central line in case they get into great vessels
arterial line do to surgical compression of heart/vessels + may have to one lung ventilate
Precordial stethoscope to detect obstruction of bronchus
Fogarty catheter for one lung ventilation
Awake intubation sitting up
RSI with inhalational
ETT tip distal to fistula and proximal to carina if possible. If this is not possible, intermittent gastrostomy venting
What are the anesthetic concerns in TE fistula?
Aspiration
PNA –> airway reactivity, sepsis, decreased compliance
Ventilation
Cardiac abnormalities
What monitors do you want for CDH or TEF?
Central line - for resuscitation, CVP and right heart function monitoring
Arterial line - for blood gas, but also because of surgical compression of heart/vessels
Precordial stethoscope for PTX, obstruction of bronchus
Pre and postductal pulse oximeters
Fiber optic near for tube checks
Esophageal or rectal temp probe
What is the anesthetic plan for pyloric stenosis?
Make sure patient is adequately resuscitated. Often have hypochloremic hyponatremic metabolic alkalosis from vomiting (BMP for electrolytes: Na > 130, chloride > 105, K > 3.0, bicarbonate < 30)
Pass NGT before induction. 2-3 X
RSI -
How will you resuscitate a newborn with pyloric stenosis and hypochloremic hyponatremic metabolic alkalosis?
NaCl with dextrose until Chloride is over 105 or urine chloride is greater than 20
Add K to solution with UOP is 1-2 ml/kg
How much dexmedetomidine can you use for pre med?
0.5-1 Mcg/kg IV
1-2 Mcg/kg intranasal
If you have no IV, what are your premed options?
IM Ketamine 2-5 mg/kg - onset 3-5 minutes, duration - 40
Intranasal dexmed 1-2 Mcg/ kg
Oral midazolam: onset 15 minutes, peak at 45, duration 2 hours
Oral fentanyl: 10 Mcg/kg
Intranasal fentanyl: 1-2 Mcg/kg
What do right to left shunts do to rate of inhalational induction?
Increases the speed of induction
Increased rate of rise of FA/Fi
What are the anesthetic considerations for BPD.
Increased airway resistance
Decreased compliance
V/Q mismatch, so low PaO2
Increased pulmonary infections
*** use nasal CPAP for recruitment!
What are anesthetic considerations for a Downs patient?
Difficult airway: Large tongue Cervical stenosis and A-A subluxation! - get X-rays to assess Obesity/OSA Sub glottic narrowing Redundant tissue --> obstruction
Difficult IV access: hypotonia and obesity, looser skin, more subq fat, and medialization of veins
Cardiac abnormalities: endocarditis cushion defects, ASD, VSD, profound bradycardia, pulmonary hypertension
GI: duodenal atresia and reflux
What are the anesthetic considerations for neuromuscular disorders?
Aspiration risk due to decreases airway reflexes, increased oral secretions
Body positioning - IV access
Resistant to NMBs (lack of functioning NMJ)
Decreased MAC and increased opioid sensitivity
Increased hypothermia
Increased blood loss, factor deficiency, TCP
Your peds patient is cold. What are you going to do?
Increase room temp Convective forced air Polymeric fabric blankets Heat lamp Heated water mattresses Plastic sheets around the head Warm IV fluids
Your peds patient bronchospasms - what do you do?
100% oxygen PPV Albuterol IV atropine 0.02mg/kg Suction Epinephrine 1 Mcg/kg
What are the anesthetic goals in noncyanotic heart lesions?
Balance of pulmonary VR and systemic VR
What are the risk factors for postoperative sleep apnea in children?
Obesity Less than 3 years old Obstruction on induction URI within last 4 weeks Nasal/craniofacial disorder Severe OSA Cor pulmonale HTN
A patient is in pain in PACU after T/A, how will you treat?
1st line: Tylenol
2nd line: oxycodone, morphine, ibuprofen
BLACKBOX on codeine
What are the anesthetic goals of congenital emphysema?
Avoiding hyperinflation of regions of the lung
Maintain spontaneous ventilation, avoid PPV, no N2O
What peds syndrome have AA Subluxation risk?
Morquio
Goldenhar
Downs
(Achondroplasia)
What peds syndrome requires awake intubation?
Pierre robin
Place nasal airway–> video laryngoscopy
Other features: posterior displacement of tongue
Opioid sensitivity
Cleft palate
Micrognathia
What are the airway concerns with MPS disorders?
Upper airway obstruction due to enlarged tongue and tissue
Difficult visibility due to lymphoid tissue infiltration
Thick secretions
Describe the circulation in a hypolplastic left heart
Systemic blood reaches RA and mixes with oxygenated blood from LA thru an ASD –> RV
2 pathways:
1. Goes to the lungs via the pulm. A
2. Goes thru the PDA retrograde flow to system
What are the anesthetic goals with hypo plastic LH?
Balance of circulation
Need to avoid an increase in pulmonary flow (keep FiO2 low, maintain preload, decrease minute ventilation and increase PaCO2 - remember PaCO2 of 28-32 causes pulmonary vasodilation)
What are the vasopressor said of choice in hypolplastic LH?
Milrinone
Phenylephrine
Phenoxybenzamine
Explain Fontan circulation, what are the anesthetic goals?
Patient now has 1 main ventricle (aorta connected to the RV)
Systemic circulation drains passively into the pulmonary artery
Pulmonary veins empty into LA
LV ejects into tricuspid to aorta
Anesthetic goals: maintain preload! Decrease PVR, maintain forward flow!
What is the initial resuscitation for a dehydrated peds patient?
20 ml/kg bolus with salt solution
10 ml/kg with albumin
What are signs of severe dehydration in a peds case?
Sucked fontanelle Dry mucous membranes UOP < 0.5 ml/kg/hr Urine specific gravity > 1.030 Weight loss of > 15%
What are the implications of an endocarditis cushion defect?
Incomplete walls
Incomplete valves
Conduction defects
What are the implications of an unrepaired endocardial cushiono defect?
Paradoxical embolization
VAE
Use a bubble trap!
How would you treat postop pain in an ENT case that you masked the whole case with no IV?
Rectal Tylenol
IM ketorolac
Intranasal fentanyl or precedex
Doing an ear tube case without an IV, patient’s heart rate drops to 4 what do you do?
Start CPR Call for help IM atropine (0.2 mg) IM epinephrine (100 Mcg) Turn off gas 100% Fi O2 Epi down ETT
How much blood would you transfuse in a neonate?
10-15 ml/kg
What is the transfusion threshold for infants with severe cadrdiopulmonary disease or neonates?
Hct less that 40-45%
What is the transfusion threshold for infants with moderate cardiopulmonary disease on CPAP or supplements O2 or major surgery?
Hct 30-35
What if the patient has stable anemia or unexplained breathing disorder? What is the transfusion threshold?
Hct 20-30
Can you give neonates “old blood”?
As long as it is within the licensed dating period it is ok to give. You do not have to use fresh blood
What is the treatment for acute chest syndrome ?
Exchange transfusion
What are the transfusion guidelines for sickle cell ?
Transfuse to maintain a HbS level below 30%, Hgb > 9 g/dl
This prevents stroke in children
What should you do if the baby’s heart rate is less than 100?
Give positive pressure ventilation
Suction
What do you do if a baby’s heart rate drops below 60?
Start chest compressions at 120 bpm
BMV with PPV
Epinephrine 10-30 Mcg/kg, 100 Mcg/kg if down ETT
Volume resuscitation of 10 ml/kg over 5-10 minutes
What is the controlled RSI technique for emergent intubation in peds?
gentle BMV with PIP less than 10-12
No cricoid pressure
O.6-0.7 mg/kg of rocuronium
In patients with pyloric stenosis, or undergoing other quick surgeries, what dose of roc can you use for intubation?
0.3-0.45 mg/kg
How will you treat postoperative pain from pyloric stenosis?
Avoid opioid due to postop apnea risk
rectal APAP and local infiltration
Could consider caudal block (1.25 ml/kg of ropi)
Give your differential for listlessness in a child
Fever Dehydration Homeopathic herbal therapy Metastatic disease to the brain (increased ICP) Seizure Anemia (bleeding) Cardiogenic shock Leukemia - immunosuppressive --> infection, bleeding,
What is an acceptable hematocrit in children?
21-26
What is different about placing a central line in a child?
More likely to pull them out!
Femoral lines are worse because of mobility issues and higher risk of thrombosis
Use Broviac catheter for cosmetics, less chance of dislodge, and less care
How would you sedate a child in the ICU.
- Benzodiazepine
Don’t use etomidate due to adrenal suppression
Don’t use propofol due to infusion syndrome
What foreign bodies are most dangerous to the lung?
Batteries –> leak acid
Oily nuts –> induce inflammation
Vegetables –> expand over time
What kind of supportive care of a kid with foreign body aspiration?
Make them calm! Supplemental O2 NPO status Beta agonists Steroids Antibiotics
What’s the oral dose of midazolam for a child 18 months - 3 years old?
0.75 mg-1mg/kg
What’s the oral dose of midazolam for a kid 3-6 years old?
0.6-0.75mg/kg
What’s the oral dose of midazolam for kids 6-10 years old?
0.5mg/kg
What’s the oral dose of midazolam for kids over 10?
0.3 mg/kg
How would you handle a complete airway obstruction on induction in a child with a foreign body?
Rapid intubation
Push foreign body down a bronchus and assume 1 lung ventilation
What is the preferred method of induction and intubation in setting of a foreign body?
Inhalational induction
Maintaining spontaneous ventilation with a ventilating bronchoscope
Emerge with mask because less stimulation of the airway
What are the expected postop complications after foreign body removal?
Vocal cord edema and stridor due to bronchoscope
Increased secretions
Bronchospasm
Consider deep extubation
What are the risk factors for postop apnea?
Post conception age 50-60 weeks (less than 44 need continuous O2 monitoring) Small for gestational age Anemia (<30%) Neuro abnormalities Sepsis
What are the critical things to know about a NICU stay?
Apnea episodes
Intubations and lengths of intubations
Methods of intubation
How long they were in NICU