Peds Flashcards
Neonate age?
<30 days
Infant age?
1-12 months
Child age?
1-12 years
Key differences between adult and peds airways:
Tongue, larynx, epiglottis, trachea and neck?
- tongue is larger
- more anterior and cephalad larynx
- long, sometimes floppy epiglottis
- short trachea and neck
What is the narrowest part in peds airway?
Subglottic region at the cricoid cartilage
What is the optimal airway potency for resuscitation?
Slightly extended (sniff position)
Infant lungs versus adult?
Stiff lungs
- lower FRC
- lower closing volume
- lower lung compliance (small alveoli)
Infant chest wall compliance versus adult?
Greater compliance
Infant O2 requirement versus adult?
2x (6ml/kg)
Infant CO2 production versus adult?
2x (ml/kg)
Newborn CO?
4ml/beat
Infants baroreceptor reflex?
Immature
What is the main determinant of CO up to age 2?
HR
Renal function at birth (4)
- Decrease GFR
- Decrease Na excretion
- Decrease concentrating ability
- Retain water
Normal function of renal at what age?
6 months
Adult function of renal at what age?
2 years
GI function (3)
- Prolonged gastric emptying
- Incompetent lower esophageal sphincter
- Increase GERD
Which hepatic phase is: toxins are altered oxidation, reduction, isomerization, and hydrolysis?
Phase 1
Which hepatic phase is: more water soluble and attach to carrier molecules to be transported out?
Phase 2
What is most important is hepatic phase 1?
P-450: endoplasmic reticulum of liver tissues
When does hepatic phase 2 mature?
Not mature for more than 2 weeks
If phase 1 is too rapid compared to phase 2, it can cause what?
Excess free radical activity
Normal hematocrit for full term?
55%
Normal hematocrit for 3 months?
30%
Normal hematocrit for 6 months?
35%
3 options for preop meds?
Versed
Clonidine
Ketamine
Versed oral dosage?
.5mg/kg
Mechanism for clonidine?
Alpha 2 adrenergic agonist
Clonidine intranasal, IM and oral dosage?
Intranasal: 2-4 mcg/kg
IM: 2mcg/kg
Oral: 4-5 mcg/kg
IM ketamine dosage?
3-4mg/kg (up to 10)
Versed or clonidine have faster onset?
Versed
Versed or clonidine level of sedation?
Clonidine better
Increased emergence agitation with versed or clonidine?
Versed
Chest wall rigidity may occur with what in neonates and infants?
Small doses of fent and other synthetic opioids
Chest wall rigidity results in what?
Hypercarbia and hypoxemia
Clear liquids NPO?
2 hrs
Breast milk NPO?
4 hrs
Formula, non human milk NPO?
6 hrs
Premature neonates avg blood volume?
95 ml/kg
Full term neonates avg blood volumes?
85 ml/kg
Infants avg blood volumes?
80 ml/kg
Adult men avg blood volumes?
75 ml/kg