Pedigrees

Question 1

What happens if gene dosage is unbalanced?

Answer 1

If the gene dosage is unbalanced, consequences can be bad
 Altered embryonic development
 Altered biological processes (extra proteins, etc)  Death
we have a set level gene expression that we need to produce the pehnotype for protein expression metabolic process
if we have to much gene expression it can be bad for health

Question 2

Dosage compensation mechanism

Answer 2

balance the expression of X-linked genes

Question 3

Double the amount of sex chromosome should mean?

Answer 3

Double the amount of sex chromosome should mean double the amount of gene expression, but that’s not the case
 In mammals, females have 2 X chromosomes while males have 1 X
 Females have twice as much X-linked expression than males