Pedigree Flashcards
What is Pedigree?
A Pedigree is a flowchart that uses symbols to show the inheritance
patterns of traits in a family over generations.
Pedigree uncovers the genotype of a particular family member.
Explain more about pedigree.
Determine the presence or absence of an allele that is responsible for a disease
Explain Autosomal Inheritance
Inheriting alleles on autosomal chromosomes not on sex chromosomes.
What is Autosomal Dominant?
Expressed when individuals
have one copy of allele.
Autosomal dominant traits pass from one parent onto their child
Does Autosomal Dominant skip generations?
No, the trait is transmitted only by affected individuals (does not skip generations)
What is Autosomal Recessive?
Expressed when an individual has 2 copies of the allele.
Autosomal recessive traits pass from both parents onto their child.
Does Autosomal Recessive skip generations?
Yes, autosomal recessive skips generations as affected individuals may not appear in every generation.
When only one copy of the allele is present, the individual is…
A carrier
What is X- Linked Recessive?
No father – son transmission
Trait can skip generations
Predominately males
affected
When the symbol is circle and shaded in, what does that mean?
Affected female
When the symbol is circle and non shaded in, what does that mean?
Unaffected female
When the symbol is square and shaded in, what does that mean?
Affected male
When the symbol is square and not shaded in, what does that mean?
Unaffected male
Autosomal Recessive parents should be.. while an their kid should be..
Parents should be heterozygous while their kid is homozygous
When the symbol is circle and grey, what does that mean?
Symptomless female
