Pediatrics Flashcards
Pediatric definitions
Neonate: birth to 1 month
Infant: 1 month to 1 year
Toddler: 1 year to 2 years
Young children 2 to 12 years
Pedi respiratory anatomy differences
6
- Larger occiput
- Larger tongue
- Narrower nasal passage
- larynx is more anterior and cephalad
- Longer epiglottis
- shorter neck and trachea
What is the most narrow point in the pedi respiratory tract?
cricoid cartilage
Respiratory Characteristics for Pedis
SWARRRRMIIING
- Short Trachea and neck
- Weaker diaphragm muscles
- Anterior/Cephalad Larynx
- Relatively longer epiglottis
- Relatively larger head / tongue
- Reduced lung compliance
- Reduced FRC
- More prominent tonsils and adenoids
- Increased RR
- Increased chest wall compliance
- Increased O2 consumption 6-8 mL/kg/min
- Narrow nasal passage
- Greater resistance to airflow
Do pedis have an increased work of breathing?
Yes
What is not fully functional in the pediatric population?
Hypoxic and hypercapnic ventilatory drives
Pediatric cardiovascular characteristics
PHIRRN
- Potential difficulty with venous and arterial cannulation
- Heart rate dependent CO
- Increased HR
- Reduced BP
- Residual fetal circulation issues
- Non-compliant LV
What are residual fetal circulation issues?
PFO
Patent ductus arterious
Is the myocardium more or less sensitive to depressant effects of anesthetics?
More
What is a concern about pediatric volume changes?
possible without accompanying HR changes
Is hypothermia or hypertherma a larger issues in the pediatric populaiton?
Hypothermia
Why is hypotherma a larger issue in pedis?
Larger body surface area
Thin skin
Low fat
What is the Mosteller formula for?
BSA calculations
What is the mosteller formula?
The SQRT of Height x Weight / 3600
BSA = m^2, Height in cm, Weight in kg
What are the three types of fat?
- White
- Brown
- Beige
What is white fat?
Most common, around organs
What is brown fat?
Energy storage
burnt to generate heat
What is beige fat?
Combination of white and brown fat
How do neonates stay warm?
brown fat metabolism
this process is inhbited by anesthetics
Pediatric renal function
- Slightly reduced
- Normal by 6 months
Can be delayed up to 2 years
Pediatric GI function
Podssible increased GERD due to pyloric stenosis
Pediatric Hepatic function
Decreased phase 2 metabolism
Reduced glycogen storage leads to possible hypoglycemia
Pediatric Drug Dosing Guide / Characteristics
WADIIF
- Weight based still used secondary to familiarity
- Adjusments based on BSA rather than mass
- Decreased protein drug binding
- Increased circulation times
- Immature biotransformation pathways
- Fluid compartment changes
5oth percentile weight formula
(Age x 2) + 9 = (kg)
Who has more total water: Adult or neonate?
Neonate
(Gradually decreased with age)
What does more TBW do to drugs?
Increased Vd
What does an increased Vd mean for drugs?
More drug leaves plasma and enteres intersticial space
Higher drug dosing needed
Drug clearance is slower due to lower metabolism
We get a fast emergence with Sevo and Des in pediatrics, what is something we need to watch out for becuae of this?
Incerased post-op delirium
What does halothane do to the myocardium?
Sensitizes it to catecholamines, so go slow
Do pedis need a higher or lower MAC?
Higher
Is respiratory depression more or less pronounced in pediatrics?
More
Nonvolatile Anesthetics in pediatrics: Propofol
- Shorter eliminaiton half-life
- Higher plasma clearance
- propofil infusion syndrom more comin in critically ill kids
- Accumulates more than opiods, verses, or precedex