Pediatric Anesthesia Flashcards
What associated abnormalities may be found in an infant with TEF/EA?
V: vertebral
A: anal
C: cardiac
T: TEF
E: esophageal atresia
R: renal and radial atresia
L: limb defects
What other condition is common in patients with a myelomeningocele?
hydrocephalus
What are the components of tetralogy of Fallot?
pulmonic stenosis
RVH
VSD
over-riding aorta
Roughly how much will transfusing a pediatric patient 4 mL/kg of pRBCs raise the Hgb?
1 g/dL
What should MAP be in neonates?
Roughly post-conceptual age
What is a normal HR in a neonate/toddler?
preterm: 150
term: 130
1-yr old: 120
toddler: 90
What is appoximate pediatric blood volume?
neonate: 90 mL/kg
infant: 80 mL/kg
toddler: 70 mL/kg
What is a normal blood gas immediately after birth?
pH: 7.20
PaO2: 50
PaCO2: 50
What is a normal umbilical venous blood gas? Umbilical arterial blood gas?
pH/PaO2/PaCO2
venous: 7.35/30/40
arterial: 7.30/20/50
When in fetal hemoglobin replaced with adult hemoglobin?
between 3 and 6 months of age
Describe the fetal circulation.
When does the ductus arteriosus usually close?
about 2 weeks of age
How can the PDA be maintained open in the setting of congenital heart disease?
prostaglandin E1 analogs (e.g., alprostadil)
Which part of the autonomic nervous system is more robust in neonates, sympathetic or parasympathetic?
parasympathetic
Why are neonates more likely to “tire out” than adults during periods of respiratory distress?
lower proportion of type I (e.g., fatigue-resistant) fibers in the diaphragm and intercostals
What is the position of the larynx in neonates vs. adults?
neonates: C4
adults: C6
How is hypoglycemia defined in the neonate?
< 30 mg/dL in the first 24 h
< 45 mg/dL after 24 h
*hypoglycemia should be corrected with a maximum concentration of D10 solution, not D25 or D50*
Where do the spinal cord and dural sac terminate in neonates vs. 1-year-olds?
Neonates: spinal cord at L3, dural sac at S4
1-year-olds: spinal cord at L1, dural sac at S2
What is bronchopulmonary dysplasia?
long-term sequelae of NRDS and mechanical ventilation of immature lungs
What lecithin/sphingomyelin ratio in amniotic fluid indicates fetal lung maturity?
L/S ratio of 2
To which classes of drugs are neonates more sensitive than adults?
opiates
benzodiazepines
barbiturates
*less sensitive to propofol and thiopental due to faster redistribution*
Why can neonates be given similar doses of non-depolarizing muscle relaxants to older children?
their larger hydrophilic compartment is balanced out by an increased sensitivity to these drugs
Why do neonates require a larger dose of succinylcholine than older children?
their larger hydrophilic compartment with similar sensitivity to the drug