ped/ger 107 final Flashcards
pharmacology definition
“The science concerned with the origin,
nature, effects, and uses of drugs”.
drugs definition
“Any chemical substance that produces
a biologic response in a living system”.
reasons of Uses of drugs:
> Aid in diagnosis of diseases
> Treatment of diseases
> Prevention of diseases
Chemical Name
first manufactured
Identifies the actual chemical structure of
the drug
Example: 2-(diphenylmethoxy)-N,N-dimethylethanamine
Sources of Drugs
Synthesized in a laboratory – epinephrine
From Mineral - iodine, zinc oxide, magnesium
sulfide
From Plant - digitalis, morphine
From Animal – hormones
From Microorganisms (fungi, molds & bacteria) penicillin, tetracycline, vaccines
Generic Name
Given to the drug when it becomes commercially available
Example: Diphenhydramine
Brand Name (Trademark, Trade Name, Proprietary Name)
Brand Name (Trademark, Trade Name, Proprietary Name)
The name given to a drug by the first company that manufactured it.
Example: Benadryl
Drugs are classified by
(1) their action or (2) by their legal classification
Oral / Peroral (PO - by mouth)
Swallowed
Sublingual =
buccal=
=under the tongue
=in the pocket between cheek and gums
topical
superficies ex: Transdermal (skin surface) Conjunctival (conjunctiva) or Intraocular (eye) Intranasal (nose) Aural (ear) Rectal Vaginal
Routes of Drug Administration
determined by:
Disease being treated
Area of the body being treated
Chemical composition of the drug
Each drug has its own characteristics
Enteric coated
prevents absorption in stomach before it gets in small intestine
parenteral
blood stream, muscle, fat The four most common: Intravenous (vein) Intradermal Subcutaneous (beneath the skin) Intramuscular (muscle)
enteral
direct to stomach
Contraindication
Any condition that renders the administration of some drug or treatment improper or undesirable.
Bolus Injection
A certain amount of a contrast media injected intravenously over a short period of time.
Bolus
An amount of a pharmaceutical preparation.
tablet scored
prepared to be cut in half or quarters
SUSPENSION
Administered orally, never intravenously!!
should be shaken
Infiltration
Diffusion of fluid into a tissue
Extravasation
Discharge or escape of fluid from a vessel into the surrounding tissue.
Edema
An abnormally large amount of fluid in
the tissues of the body. Swelling.
Ampule
Small, sealed glass container that holds a single dose of a parenteral solution in a sterile condition.
Vial
A small glass bottle (container) containing many doses of a
drug.
Anaphylaxis
Allergic shock.
PHARMACOKINETICS
The study of how a drug is absorbed into the
body, circulates within the body, and exits
the body (what the drug does to the body).
4 processes :
absorption (how enters the blood)
distribution (circulatory lymphatic system)
metabolism (how body transform drug, liver)
excretion (out, kidneys)
PHARMACODYNAMICS
The study of the effect of the drugs on the body.
Receptor sites
a protein molecule located on the cell’s surface or within the cell’s cytoplasm that binds to a specific factor such as a hormone, antigen, or neurotransmitter.
most common drugs, blinds to receptor sites on cells.
epinephrine is an emergency drug commonly found on a cart. Which of the following is an indication for its use?
cardiac arrest and anaphylaxis
most common unit of measurement
mL = 1/1000
subcutaneous
drug placed under skin into the tissue that lies beneath the epidermal layers
means that the drug is administered by a route other than the gastrointestinal tract
parenteral
Antagonist
A drug that is designed to inhibit or counteract
effects produced by other drugs or desired effects
caused by cellular components during illness.
Agonist
A drug that produces a specific action and promotes the desired result.
QOD QD BID TID QID PO NPO
EVERY OTHER DAY EVERYDAY TWO TIMES A DAY THREE TIMES A DAY FOUR TIMES A DAY BY MOUTH NOTHING BY MOUTH
contrast media purpose
enhance the low subject contrast of anatomic structures
To visualize anatomic structures that are not normally seen on a diagnostic medical image.
if barium sulfate is administered by a patient with perforation of the colon, will cause
peritonitis
who discovered air can be used as contrast agent
Walter dandy
credited for discovering the disease of the GI tract
Walter cannon
general term for the material to be visualize anatomic structures that are not normally seem on x-rays
contrast media
all show radiographic densities on x-rays except
sulphur
lowest contrast among the 5 densities are water and..
fat
contrast media are generally classified as
negative and positive
weak x-ray photons are easily absorb by __ contrast media
radiopaque
flow rate of barium through a tubing and also influences the mucosal coating of intestinal lumen?
viscosity
a complication related to the administration of barium sulfate during GI examination is__ of the colon
perforation
anatomic structures are filled with __ contrast agents appears dark (increase density on radiographs, they are also called?
radiolucent, negative
radiopaque contrast agents are composed of elements with __ atomics numbers
high
correct order scheduling patient types
elderly and debilitated, diabetics, children, relatively healthy adults.
contrast exam that is time sequenced procedures
biliary and IVP/IVU
what radiographic exams of the esophagus, stomach, and small intestines have in common?
they are all administered orally
CT studies of GI tract should be perform before other exams requiring the use of barium sulfate
true
when scheduling multiple exams, contrast exam are
last
appropriate patient preparation for contrast enema
take a laxative or cleansing enema
consume large amounts of fluids
maintain a fluid diet prior the examination
patient preparation for Upper Gastrointestinal (UG) exam
patient should consume nothing by mouth on the night prior to procedure