PE, PTx, Pleural Effusion Flashcards
PE
diagnostic tools
- Wells Score
- 1Wells Negative then rule out with PERC
- PERC normal then nil further
- 3 PERC positive then D dimer to rule out
- Wells Positive then imaging
Most common sx of PE
dyspnoea
chest pain
sx of DVT
hemoptysis - rare
Mx DVT
distal –> 15% extension, treat for 6/52
prox - treat for 3/12
PE mx
Cleaxane 24-48/42
NOAC
Shock - alteplase
PE risk factors
previous VTE active cancer unprovoked VTE in the last 3/12 male PROX DVT Thrombophilias
Ptx Classification and Clinical Severity Classification
Primary - no underlying lung dx. Secondary - ?COPD, ILD etc
Clinically
- size (<2cm or more)
- symptoms
- stable or not
PTx management
Clincally stable, <2cm –> home with repeat CXR
Small but unstable or large but stable –> aspiration. unsuccessful asp –> ICC
Ptx safe to fly - time
2/52
Ptx - recurrence rate and factors
30-50% recurrence. Recommend pleurodesis after first recurrence
RF - smoker
Lights criteria
- Pleural fluid Protein /Serum Protein ratio >0.5
- Pleural Fluid LDH /Serum LDH ratio >0.6
- Pleural Fluid LDH > 2/3 upper limit normal serum level
pleural fluid - other biomarkers
CRP - infection BNP - Heart failure ADA (adenosine deaminase) - TB. If very elevated then empyema or lymphoma Cytology (40% will be missed) Pleural elastase - trapped lung
Mx of empyema
Drain
MIST2 Trial - add DNAse to tPA