PCOS

Question 1

Features

Answer 1

subfertility and infertility
menstrual disturbances: oligomenorrhoea and amenorrhoea
hirsutism, acne (due to hyperandrogenism)
obesity
acanthosis nigricans (due to insulin resistance)

Question 2

ivg

Answer 2

pelvic ultrasound - multiple cysts
raised LH:FSH 0 with the LH very raised
testosterone, prolactin normal / mildly elevated

Question 3

diagnostic criteria

Answer 3

rotterdam criteria -
infrequent or no ovulation
signs of hyperandrogenism (such as hirsutism, acne, or elevated levels of total or free testosterone)
polycystic ovaries on ultrasound scan (defined as the presence of ≥ 12 follicles (measuring 2-9 mm in diameter) in one or both ovaries and/or increased ovarian volume > 10 cm³

Question 4

mx

Answer 4

weight loss
COCP
topical eflornithine for hirsutism
clomifene for infertility along with metformin in obese patients